Mobile element type:
Transposon
Name:
Tn6260
Synonyms:
Accession:
Tn6260-KX470419
Family:
Tn554
Group:
First isolate:
Yes
Partial:
ND
Evidence of transposition:
ND
Host Organism:
Listeria monocytogenes 6179
Date of Isolation:
2013
Country:
Molecular Source:
chromosome
ORF Summary
| Name | Associated TE | Coordinates | Orientation | Class | Subclass |
|---|---|---|---|---|---|
| tnpA | Tn6260 | 136-1221 | + | Transposase | |
| tnpB | Tn6260 | 1218-3116 | + | Transposase | |
| lnuG (ARO:3004085) | Tn6260 | 3812-4615 | + | Passenger Gene | Antibiotic Resistance |
ORF Details
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | tnpA | TnpA | Tn6260 | 361 | 136-1221 | + |
|---|
| Class: | Transposase | ||||||||||
| Protein Sequence: | MKVQRIKVEN KPYPLYLLLD EEYQVIEPVM RFIKYLDNTG KSPNTIKAYC YHLKLLYEFM EQRGITLNDI NFEKLADFVG WLRYPTAANV IDLQSKEAIR EETTVNTILN AVMSYLEYLS RLGEFKSIDV FKQAKGRNFK GFLHHINKGK YQKNILKLRV KKKQIRTLTS EEVKQIIDAC HTKRDKLILM LMYEGGLRIG EVLSLRLEDI ATWDNQIHLT PRDVNVNEAY IKLRKERTIH VSKELMALYT DYLVYEYGED LEHDYVFISL KEGYFGKPLK YQSVLDLVRR IVKRTRIEFT PHMLRHTHAT QLIRDGWDVA HVQKRLGHAH VQTTLNTYVH LSDQDMKNEF NKYLERKEHK K |
||||||||||
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | tnpB | TnpB | Tn6260 | 632 | 1218-3116 | + |
|---|
| Class: | Transposase | ||||||||||
| Protein Sequence: | MNDSSKRKII SQSEISKKIA AMNEELQGFW ANNSWDIRKC PHPSAIELSK NPTLRNRWVR FERVKNLWLR TELKYFYFYH LNNGIWNAKT VWIRKGTVIN RMLDFLDLKY PNITSITEVP IKKAMTEYRT YLTEQGVRIT TTNYKITANQ EKIAVEANSY YVTNLKQFME FYEDFYFDGE EWDKDIWDRR KLPLPDDKVN PTQYEYVINF KGVRNTYFKQ LVKRYCKLRL NTDSFSYVCD IAQKLKEFFN FLDMNFKHVQ RINQLTRMEI EAYLSELNMM GIKPSTITGR ISILEGLFST LLRLEWNDIP SKVLIYPEDY PKIPRAKPRF IDEYVLEQLN SHLDKLPEYI ATMTMIVQEC GMRISELCTL KKGCLLEDKD GDYFLKYYQW KMKKEHIVPI SKEVALLIKV REDKVSWEFP DSEYLFPRKD GSPLKQETFR DELNKLAYEQ KIVDKSGEIY RFHAHAFRHT VGTRMINNGV PQHIVQKFLG HESPEMTSRY AHIFDETLKA EFTKFKEKLV TNNGDIIELD NDNEVDDVDL QWFKKNINAQ VLPNGYCRLP VIAGSCPHAN ACLDCTHFCT SKQFLSQHEE QLNRTEELLA VAKEKQWQRQ IETNNRVKER LEQIIGSLKG IS |
||||||||||
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | lnuG (ARO:3004085) | LnuG | Tn6260 | 267 | 3812-4615 | + |
|---|
| Class: | Passenger Gene | ||||||||||
| Subclass: | Antibiotic Resistance | ||||||||||
| Function: | antibiotic inactivation (ARO:0001004) | ||||||||||
| Sequence Family: | lincosamide nucleotidyltransferase (LNU) (ARO:3000221) | ||||||||||
| Target: | lincosamide antibiotic (ARO:0000017) | ||||||||||
| Comment: | perfect match to reference sequence for ARO:3004085 (Bitscore 538) | ||||||||||
| Protein Sequence: | MLKQKELMAR VKELVQSDER ISACMMYGSF TKGEGDQYSD IEYYVFLKDD TISTFDSAKW LNEVASYTLL YQNEYGTEVV IFENLIRGEF HFLSENEMNI IPSFKESGYI PDTKAMFIYD ETGQLELYLS ELEGPGPNRL TEENVNFLLN NFSNLWLMGI NVLKRGENAR SLELLSQLQK NILQLIRIAE ENADNWFNMT KNLEKEISPE NYEKFKKTTA RLNELELYEA YKNSLLLVME LRNLVEKQYQ LTISDDFLGK LFNYMNE |
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1. Zhu XQ, Wang XM, Li H, Shang YH, Pan YS, Wu CM, Wang Y, Du XD, Shen JZ.
Novel lnu(G) gene conferring resistance to lincomycin by nucleotidylation, located on Tn6260 from Enterococcus faecalis E531.. J Antimicrob Chemother. 2017 Apr 1;72(4):993-997. doi: 10.1093/jac/dkw549. PubMed ID:
28039271
.