Mobile element type:
Transposon
Name:
Tn559
Synonyms:
Accession:
Tn559-FN677369
Family:
Tn554
Group:
First isolate:
Yes
Partial:
ND
Evidence of transposition:
Yes
Host Organism:
Staphylococcus aureus ST398
Date of Isolation:
2010
Country:
Germany
Molecular Source:
genome
| Name | Associated TE | Coordinates | Orientation | Length | Sequence |
|---|---|---|---|---|---|
| att | Tn559 | 1-6 | + | 6 | GATGTA |
| att | Tn559 | 4290-4295 | + | 6 | CAAGTT |
ORF Summary
| Name | Associated TE | Coordinates | Orientation | Class | Subclass |
|---|---|---|---|---|---|
| tnpA | Tn559 | 141-1226 | + | Transposase | |
| tnpB | Tn559 | 1223-3115 | + | Transposase | |
| tnpC | Tn559 | 3122-3499 | + | Accessory Gene | Helper |
| dfrK (ARO:3002869) | Tn559 | 3619-4110 | + | Passenger Gene | Antibiotic Resistance |
ORF Details
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | tnpA | TnpA | Tn559 | 361 | 141-1226 | + |
|---|
| Class: | Transposase | ||||||||||
| Protein Sequence: | MRVQRIEVEN KPYPLYLLLD KEYQLIEPVM KFIKYLDNTG KSPNTIKAYC YHLKLLYEFM EQRGVILNDI NFELLADFVG WLRYPTANNV IDLQSKEAIR EETTVNTILN AVMSFLDYLS RLGEFKSIDV FKQAKGRNFK GFLHHVNKGR YQKNVLKLRV KKKQIRTLTA EEVKQIIDAC HTKRDKLILM LMYEGGLRIG EVLSLRLEDI ATWDNQIHLT PRDVNVNEAY IKLRKERTIH VSKELMSLYT DYLVYEYSEE LEHDYVFISL KEGYFGKPLK YQSVLDLVRR IVKRTGIEFT SHMLRHTHAT QLIREGWDVA FVQKRLGHAH VQTTLNTYVH LSDQDMKNEF NKYLERKEHK K |
||||||||||
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | tnpB | TnpB | Tn559 | 630 | 1223-3115 | + |
|---|
| Class: | Transposase | ||||||||||
| Protein Sequence: | MNASSKRKII SQSEISKKIA VMNEEMQGFW ANNSWDIRKC PHPSAIELSK NPALRNRWVR FERVKNLWLR TELKYFYFYH LNNRIWNAKT VWIRKGTVIN KMLDFLDLKY PSITSITEVP IDKAMTEYRT YLTKQGVRIT TTNYKITANQ EKTPVKANSY YVTNLKQFIE FYEDFYFDGE EWDKDVWDRR NLPLPDDKVN PTQYEYTINF KGFRNTYFKQ LVKRYCKLRL NMDSFSYVSD IAQKLKEFFN FLDIKFKHVQ RVHQLTRVEI EAYLSELNMM GIKPSTITGR ISILEGLFST LHRLEWDDVP SKLLIYPEDY PKIPRAKPRF IDEFVLEQLN SHLDKLPEYI ATMTMIVQEC GMRISELCTL KKGCLLEDKD GDYFLKYYQW KMKKEHIVPI SKEVALLIKV REDKVSEEFP DSEYLFPRKD GSPLKQETFR GELNKLAYEQ NIVDKSGEIY RFHAHAFRHT VGTRMINNGV PQHIVQKFLG HESPEMTSRY AHIFDETLKN EFTKFQEKLV TNNGDVLNLD DDSEVDDVEL QWFKKNINAQ VLPNGYCRLP VIAGGCPHAN ACLDCTHFCT SKQFLPQHEE QLERTEELLT IAKDKQWQRQ IETNSRVKER LEQIIGSLTG |
||||||||||
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | tnpC | TnpC | Tn559 | 125 | 3122-3499 | + |
|---|
| Class: | Accessory Gene | ||||||||||
| Subclass: | Helper | ||||||||||
| Sequence Family: | Tn554_family | ||||||||||
| Comment: | target specificity and orientation | ||||||||||
| Protein Sequence: | MDKQVRNTTE IVRLAKQKSQ KTREKVDKAI SKFSIEGKAI NFNSIAKEAN VSKSWLYKEH DIRQRIESLR ERQITSNVVS KPKKSSRSEE ILIKTLKRRV MELEKENKKL QNQIQKLYGD LYNKE |
||||||||||
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | dfrK (ARO:3002869) | DfrK | Tn559 | 163 | 3619-4110 | + |
|---|
| Class: | Passenger Gene | ||||||||||
| Subclass: | Antibiotic Resistance | ||||||||||
| Function: | antibiotic target replacement (ARO:0001002) | ||||||||||
| Sequence Family: | trimethoprim resistant dihydrofolate reductase dfr (ARO:3001218) | ||||||||||
| Target: | diaminopyrimidine antibiotic (ARO:3000171) | ||||||||||
| Comment: | perfect match to reference sequence for ARO:3002869 | ||||||||||
| Protein Sequence: | MKVSLIAAMD KNRVLGKEND IPWRIPKDWE YVKNTTKGYP IILGRKNLES IGRALPGRRN IILTRDKGFS FNGCEIVHSI EDVFEICNNE EEIFIFGGEQ IYNLFLPYVE KMYITKIHYE FEGDTFFPEV NYEEWSEVSV TQGITDEKNP YTYYFHIYER KAY |
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1. Kadlec K, Schwarz S.
Identification of the novel dfrK-carrying transposon Tn559 in a porcine methicillin-susceptible Staphylococcus aureus ST398 strain.. Antimicrob Agents Chemother. 2010 Aug;54(8):3475-7. doi: 10.1128/AAC.00464-10. Epub 2010 May 24. PubMed ID:
20498309
.