Mobile element type:
Transposon
Name:
Tn554Cad
Synonyms:
Accession:
Tn554Cad-AB037671.1
Family:
Tn554
Group:
First isolate:
Yes
Partial:
ND
Evidence of transposition:
ND
Host Organism:
Staphylococcus aureus85_2082
Date of Isolation:
2001
Country:
New zealand
Molecular Source:
chromosomeSSCmec
ORF Summary
| Name | Associated TE | Coordinates | Orientation | Class | Subclass |
|---|---|---|---|---|---|
| tnpB | Tn554Cad | 210-2102 | + | Transposase | |
| tnpC | Tn554Cad | 2109-2486 | + | Accessory Gene | Helper |
| cadC | Tn554Cad | 2724-3089 | + | Passenger Gene | Heavy Metal Resistance |
| cadA | Tn554Cad | 3082-5496 | + | Passenger Gene | Heavy Metal Resistance |
| cadD | Tn554Cad | 5535-6194 | + | Passenger Gene | Heavy Metal Resistance |
ORF Details
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | tnpB | TnpB | Tn554Cad | 630 | 210-2102 | + |
|---|
| Class: | Transposase | ||||||||||
| Protein Sequence: | MNASSKRKII SQSEISKKIA VMNEEMQGFW ANNSWDIRKC PHPSAIELSK NPALRNRWVR FERVKNLWLR TELKYFYFYH LNNGIWNAKT VWIRKGTVIN KMLDFLDLKY PSITSITEVP IDKAMTEYRT YLTKQGVRIT TTNYKITANQ EKTPVKANSY YVTNLKQFIE FYEDFYFDGE EWDKDVWDRR NLPLPDDKVN PTQYEYTINF KGFRNTYFKQ LVKRYCKLRL NMDSFSYVSD IAQKLKEFFN FLDIKFKHVQ RVHQLTRVEI EAYLSELNMM GIKPSTITGR ISILEGLFST LHRLEWDDVP SKLLIYPEDY PKIPRAKPRF IDEFVLEQLN SHLDKLPEYI ATMTMIVQEC GMRISELCTL KKGCLLEDKD GDYFLKYYQW KMKKEHIVPI SKEVVLLIKV REDKVSEEFP DSEYLFPRKD GSPLKQETFR GELNKLAYEQ NIVDKLGEIY RFHAHAFRHS VGTRMINNGV PQHIVQKFLG HESPEMTSRY AHIFDETLKN EFTKFQEKLV TNNGDVLNLD DDSEVDDVEL QWFKKNINAQ VLPNGYCRLP VIAGGCPHAN ACLDCTHFCT SKQFLPQHEE QLERTEELLT IAKDKQWQRQ IETNSRVKER LEQIIGSLTG |
||||||||||
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | tnpC | TnpC | Tn554Cad | 125 | 2109-2486 | + |
|---|
| Class: | Accessory Gene | ||||||||||
| Subclass: | Helper | ||||||||||
| Sequence Family: | Tn554_family | ||||||||||
| Comment: | target specificity and orientation | ||||||||||
| Protein Sequence: | MNKQVRNTTE IVRLAKQKSQ KTREKVDKAI SKFSIEGKAI NFNSIAKEAN VSKSWLYKEH DIRQRIESLR ERQITSNVVS KPKKSSRSEE ILIKTLKRRV MELEKENKKL QNQIQKLYGD LYNKE |
||||||||||
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | cadC | CadC | Tn554Cad | 121 | 2724-3089 | + |
|---|
| Class: | Passenger Gene | ||||||||||
| Subclass: | Heavy Metal Resistance | ||||||||||
| Target: | Cadmium | ||||||||||
| Comment: | cadmium efflux system repressor | ||||||||||
| Protein Sequence: | MTKDMCEVTY IHEDKVNRAK KDLAKQNPMD VAKVFKALSD DTRVKIAYVL SLEGELCVCD VANIIESSTA TASHHLRLLK NLGIAKYRKE GKLVYYSLDD EHVKQLVEKA FLHQREVASI G |
||||||||||
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | cadA | CadA | Tn554Cad | 804 | 3082-5496 | + |
|---|
| Class: | Passenger Gene | ||||||||||
| Subclass: | Heavy Metal Resistance | ||||||||||
| Target: | Cadmium | ||||||||||
| Comment: | P-type cadmium-efflux ATPase | ||||||||||
| Protein Sequence: | MDSSTKTLTE DKQVYRVEGF SCANCAGKFE KNVKELSGVH DAKVNFGASK IDVFGSATVE DLEKAGAFEN LKVAPEKARR RVEPVVTEDK NVYRVEGFSC ANCAGKFEKN VKQLAGVQDA KVNFGASKID VYGNTSVEEL EKAGAFENLK VIPEKLANPS IQAVKEDTKA PKEEKIPFYK KHSTLLFATL LIAFGYLSHF VNGEDNLVTS MLFVSSIVIG GYSLFKVGFQ NLIRFDFDMK TLMTVAVIGA AIIGEWAEAS IVVILFAISE ALERFSMDRA RQSIRSLMDI APKEALVRRN GQEIMIHVDD IAVGDIMIVK PGEKIAMDGI IINGVSAVNQ AAITGESVPV AKTVDDEVFA GTLNEEGLLE VKITKYVEDT TISKIIHLVE EAQGERAPAQ AFVDKFAKYY TPIIMVIAAL VAVVPPLFFG GSWDTWVYQG LAVLVVGCPC ALVITTPISI VSAIGNAAKK GVLIKGGVYL EELGAIKAIA FDKTGTLTKG VPVVTDFKVL NDQVEEKELF SIITALEYRS QHPLASAIMK KAEQDNITYS DVRVKDFTSI TGRGIQGNID GTTYYIGSPR LFKELNVSDF SLEFENKVKV LQNQGKTAMI IGTDQTILGV IAVADEVRET SKNVILKLHQ LGIKQTIMLT GDNQGTAEAI GAHVGVSDIQ SELLPQDKLD YIKKMKAEHG NVAMIGDGVN DAPALAASTV GIAMGGAGTD TAIETADIAL MGDDLSKLPF AVRLSRKTLN IIKANITFAI GIKIIALLLV IPGWLTLWIA ILSDMGATIL VALNSLRLMR VKDK |
||||||||||
| Gene Name | Protein Name | Associated TE | Gene Length | Coordinates | Strand | cadD | CadD | Tn554Cad | 219 | 5535-6194 | + |
|---|
| Class: | Passenger Gene | ||||||||||
| Subclass: | Heavy Metal Resistance | ||||||||||
| Sequence Family: | Cad (Pfam:PF03596) | ||||||||||
| Target: | Cadmium | ||||||||||
| Comment: | cadmium resistance transporter (or sequestration) family protein | ||||||||||
| Protein Sequence: | MKKSPIPKIF GDDKMIATIL TATAVYVATG IDYLVILILL FSQVKKGQVK HIWIGQYIGT AIVIGASLLV AQGVVNLIPQ QWVIGLLGLL PLYLGVKIWI KGEEDEDESS ILSLFSSGKF NQLFLTMIFI VLASSADDFS IYIPYFTTLS MSEIFIVTIV FLIMVGVLCY VSYRLASFDF ISETIEKYER WIVPIVFIGL GIYILFENGT FNALISFLL |
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1. Ito T, Katayama Y, Asada K, Mori N, Tsutsumimoto K, Tiensasitorn C, Hiramatsu K.
Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus.. Antimicrob Agents Chemother. 2001 May;45(5):1323-36. doi: 10.1128/AAC.45.5.1323-1336.2001. PubMed ID:
11302791
.
2. Ito T, Okuma K, Ma XX, Yuzawa H, Hiramatsu K. Insights on antibiotic resistance of Staphylococcus aureus from its whole genome: genomic island SCC.. Drug Resist Updat. 2003 Feb;6(1):41-52. doi: 10.1016/s1368-7646(03)00003-7. PubMed ID: 12654286 .
2. Ito T, Okuma K, Ma XX, Yuzawa H, Hiramatsu K. Insights on antibiotic resistance of Staphylococcus aureus from its whole genome: genomic island SCC.. Drug Resist Updat. 2003 Feb;6(1):41-52. doi: 10.1016/s1368-7646(03)00003-7. PubMed ID: 12654286 .