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  Internal Repeats  
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Sequence File (FASTA format)     



Transposon
Name: Tn6238
Family: Tn3        Group: Tn3
Evidence of Transposition: no
 Host     

Host Organism:Klebsiella pneumoniae KpF7 Molecular Source:plasmid pMPQDC1
Place of Origin:Argentina Date of Isolation:2015

 Map     



 Terminal Inverted Repeats (IR)     

IRL (Length: 38 bp)GGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAAG
IRR (Length: 38 bp)GGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAAG

 Sequence     
DNA SequenceLength  7995 
--------10 --------20 --------30 --------40 --------50 --------60 --------70 --------80 --------90 -------100
GGGGTCTGAC GCTCAGTGGA ACGAAAACTC ACGTTAAGGG ATTTTGGTCA TGAGATTATC AAAAAGGATC TTCACCTAGA TCCTTTTAAA TTAAAAATGA 100
AGTTTTAAAT CAATCTAAAG TATATATGAG TAAACTTGGT CTGACAGTTA CCAATGCTTA ATCAGTGAGG CACCTATCTC AGCGATCTGT CTATTTCGTT 200
CATCCATAGT TGCCTGACTC CCCGTCGTGT AGATAACTAC GATACGGGAG GGCTTACCAT CTGGCCCCAG TGCTGCAATG ATACCGCGAG ACCCACGCTC 300
ACCGGCTCCA GATTTATCAG CAATAAACCA GCCAGCCGGA AGGGCCGAGC GCAGAAGTGG TCCTGCAACT TTATCCGCCT CCATCCAGTC TATTAATTGT 400
TGCCGGGAAG CTAGAGTAAG TAGTTCGCCA GTTAATAGTT TGCGCAACGT TGTTGCCATT GCTGCAGGCA TCGTGGTGTC ACGCTCGTCG TTTGGTATGG 500
CTTCATTCAG CTCCGGTTCC CAACGATCAA GGCGAGTTAC ATGATCCCCC ATGTTGTGCA AAAAAGCGGT TAGCTCCTTC GGTCCTCCGA TCGTTGTCAG 600
AAGTAAGTTG GCCGCAGTGT TATCACTCAT GGTTATGGCA GCACTGCATA ATTCTCTTAC TGTCATGCCA TCCGTAAGAT GCTTTTCTGT GACTGGTGAG 700
TACTCAACCA AGTCATTCTG AGAATAGTGT ATGCGGCGAC CGAGTTGCTC TTGCCCGGCG TCAACACGGG ATAATACCGC GCCACATAGC AGAACTTTAA 800
AAGTGCTCAT CATTGGAAAA CGTTCTTCGG GGCGAAAACT CTCAAGGATC TTACCGCTGT TGAGATCCAG TTCGATGTAA CCCACTCGTG CACCCAACTG 900
ATCTTCAGCA TCTTTTACTT TCACCAGCGT TTCTGGGTGA GCAAAAACAG GAAGGCAAAA TGCCGCAAAA AAGGGAATAA GGGCGACACG GAAATGTTGA 1000
ATACTCATAC TCTTCCTTTT TCAATATTAT TGAAGCATTT ATCAGGGTTA TTGTCTCATG AGCGGATACA TATTTGAATG TATTTAGAAA AATAAACAAA 1100
TAGGGGTTCC GCGCACATTT CCCCGAAAAG TGCCACCTGA CGTCTAAGAA ACCATTATTA TCATGACATT AACCTATAAA AATAAGCGTA TCACGAGGCC 1200
CTTTCGTCTT CAAGAATTTT ATAAACCGTG GAGCGGGCAA TACTGAGCTG ATGAGCAATT TCCGTTGCAC CAGTGCCCTT CTGATGAAGC GTCAGCACGA 1300
CGTTCCTGTC CACGGTACGC CTGCGGCCAA ATTTGATTCC TTTCAGCTTT GCTTCCTGTC GGCCCTCATT CGTGCGCTCT AGGATCCTCC GGCGTTCAGC 1400
CTGTGCCACA GCCGACAGGA TGGTGACCAC CATTTGCCCC ATATCACCGT CGGTACTGAT CCCGTCGTCA ATAAACCGAA CCGCTACACC CTGAGCATCA 1500
AACTCTTTTC ATGATATATC TCCCAATTTG TGTAGGGCTT ATTATGCACG CTTAAAAATA ATAAAAGCAG ACTTGACCTG ATAGTTTGGC TGTGAGCAAT 1600
TATGTGCTTA GTGCATCTAA CGTTCAAGGT GAGCGGACTC GCGCGGCTTT ATGCGCGAGG TCCGCTCGAG CGCAGGGTTA TGCATCTGCT CTCGATGACG 1700
CCACATATCA TTTGTTACCC ATCAACACGG GTAATTCCAC GAGAATATCC TCTCGTGCTT TAGACCCGCC GGGAATATCG GACTTTTCCT TTCCTATTTC 1800
CAATCGGGCG AAAACAACTT GCCGTCCGTT TTTTTCAGCC CAGCCCACGA ACCAGCCCTG CGGACGACTT TCATTTATCT TGCCGTTATT GTCCCGAAGC 1900
CAGCCGCTGC CGCTTTTTCC ATGTACAGCC CATCCTTCGG CTGCCTGGTA CTGCGGGATT GTGGCATACG CCATGTCATA AGCCGCTTCG GATACAGGCA 2000
GCTTATGCGC GACAAAGCGT AGAAGAAACT GAATTTGCTC CTTGGGAGAT ATGGTGAGCG ACGACATCAG CCATGACTGG GTCAAGCCGT TATGCTTCCC 2100
CGAGTCACCG GAAACATCTT GATTACCGTA CTCAAATTTC TTTACGTATT CCGTGAACCG ATCAACTCCC AGACGGCTTG TTAATTGCTG CGAGAACCAG 2200
ACAACAGAGT CGCTTTGCCA TAGCGCCGGA TAGACTTGTT TGTATGTGCG ATCTCTCGGA GACGGGTTGT ATTCCGGCTT CAATTCCCAC GTAGGTGATT 2300
TTGGCGACTG CAAGATTCCA CTATCAAACC CCATGATTGC CAATGGAAGT TTAAAAGACG AGCACGGAGA CACACGACGG GCACATTCTC CGGTCTCATA 2400
TAAGGTATTT CCGGTAATGG CGTCTGCGAT GATGGTGCAT TTAAGCGTTT CAACCTCATC AGAAGCCACG GAACTGATTG GGAGAGTGGC GGAAACGAAC 2500
ACCAACATAT GCAGCAGCAA AATTTTTTTC ATCAAGGTAT CCTTCATTGC TCCGCTGTGC GCTTAATAGG TGCATAACTT TGTTTTAGAC ATTATTTGCC 2600
GACTACCTTG GTGATCTCGC CTTTCACGTA GTGAACAAAT TCTTCCAACT GATCTGCGCG CGAGGCCAAG CGATCTTCTT GTCCAAGATA AGCCTGCCTA 2700
GCTTCAAGTA TGACGGGCTG ATACTGGGCC GGCAGGCGCT CCATTGCCCA GTCGGCAGCG ACATCCTTCG GCGCGATTTT GCCGGTTACT GCGCTGTACC 2800
AAATGCGGGA CAACGTAAGC ACTACATTTC GCTCATCGCC AGCCCAGTCG GGCGGCGAGT TCCATAGCGT TAAGGTTTCA TTTAGCGCCT CAAATAGATC 2900
CTGTTCAGGA ACCGGATCAA AGAGTTCCTC CGCCGCTGGA CCTACCAAGG CAACGCTATG TTCTCTTGCT TTTGTCAGCA AGATAGCCAG ATCAATGTCG 3000
ATCGTGGCTG GCTCGAAGAT ACCTGCAAGA ATGTCATTGC GCTGCCATTC TCCAAATTGC AGTTCGCGCT TAGCTGGATA ACGCCACGGA ATGATGTCGT 3100
CGTGCACAAC AATGGTGACT TCTACAGCGC GGAGAATCTC GCTCTCTCCA GGGGAAGCCG AAGTTTCCAA AAGGTCGTTG ATCAAAGCTC GCCGCGTTGT 3200
TTCATCAAGC CTTACGGTCA CCGTAACCAG CAAATCAATA TCACTGTGTG GCTTCAGGCC GCCATCCACT GCGGAGCCGT ACAAATGTAC GGCCAGCAAC 3300
GTCGGTTCGA GATGGCGCTC GATGACGCCA ACTACCTCTG ATAGTTGAGT CGATACTTCG GCGATCACCG CTTCCCTCAT GATGTTTAAC GTTTGACATG 3400
AGGGGCGGCC AAGGGCGCCA GCCCTTGGAC GTCCCCCTCG ATGGAAGGGT TAGGCAACAC TGCGTGTTCG CTCGAATGCC TGGCGTGTTT GAACCATGTA 3500
CACGGCTGGA CCATATGGGG TGGTTACGGT ACCTTGCCTC TCAAACCCCG CTTTCTCGTA GCATCGGATC GCTCGCAAGT TGCTCGGCGA CGGGTCCGTT 3600
TGGATCTTGG TGACCTCGGG ATCATTGAAC AGCAACTCAA CCAGAGCTCG AACCAGCTTG GTTCCCAAGC CTTTGCCCAG TTGTGATGCA TTCGCCAGTA 3700
ACTGGTCTAT TCCGCGTACT CCTGGATCGG TTTCTTCTTC CCACCTTCCG TCCCCGCTTC CAAGAGCAAC GTACGACTGG GCATACCCAA TCGGCTCTCC 3800
ATTCAGCATT GCAATGTATG GAGTGACGGA CTCTTGCGCT AAAACGCTTG GCAAGTACTG TTCCTGTACG TCAGCAAGTG TCGGGCGTGC TTCTTCTCCG 3900
CCCCACCACT CGACGATATG AGATCGATTT AGCCACTCAT AGAGCATCGC AAGGTCATGC TCAGTCATGA GGCGCAGTGT GACGGAATCG TTGCTGTTGG 4000
TCACGATGCT GTACTTTGTG ATGCCTAACT TTGTTTGGAA ATGTTGAATA CTCATACTCT TCCTTTTTCA ATATTATTGA AGCATTTATC AGGGTTATTG 4100
TCTCATGAGC GGATACATAT TTGAATGTAT TTAGAAAAAT AAACAAATAG GGGTTCCGCG CACATTTCCC CGAAAAGTGC CACCTGACGT CTAAGAAACC 4200
ATTATTATCA TGACATTAAC CTATAAAAAT AGGCGTATCA CGAGGCCCTT TCGTCTTCAA GAATTTTATA AACCGTGGAG CGGGCAATAC TGAGCTGATG 4300
AGCAATTTCC GTTGCACCAG TGCCCTTCTG ATGAAGCGTC AGCACGACGT TCCTGTCCAC GGTACGCCTG CGGCCAAATT TGATTCCTTT CAGCTTTGCT 4400
TCCTGTCGGC CCTCATTCGT GCGCTCTAGG ATCCTCCGGC GTTCAGCCTG TGCCACAGCC GACAGGATGG TGACCACCAT TTGCCCCATA TCACCGTCGG 4500
TACTGATCCC GTCGTCAATA AACCGAACCG CTACACCCTG AGCATCAAAC TCTTTTATCA GTTGGATCAT GTCGGCGGTG TCGCGGCCAA GACGGTCGAG 4600
CTTCTTCACC AGAATGACAT CACCTTCCTC CACCTTCATC CTCAGCAAAT CCAGCCCTTC CCGATCTGTT GAACTGCCGG ATGCCTTGTC GGTAAAGATG 4700
CGGTTAGCTT TTACCCCTGC ATCTTTGAGC GCTCTGATCT GAATATCGAG GGACTGCTGG CTGGTTGAGA CCCGCGCATA ACCAAAAATT CGCATAAAAA 4800
TGTACCTTAA ATCGAATATC AGACACGATG TGTCTATTAT GCCAAAATGA CGATTTAATG GACACTCAAA CGAAGCCGTT TTACTATGTC TGATAATTTA 4900
TAATATTTCG AACGGTTGCA GTTGTGTTAA AAAAGCCGTC AGGCAGGGAG GCCGATATGC CCGTTGATTT TTTGACCACT GAGCAGGTTG AGAGTTATGG 5000
CAGGTTCACT GGCGAACCCG ATGAACTTCA GCTGGCGCGT TATTTTCATC TTGATGAAGC GGATAAAGAA TTTATCGGGA AAAGCCGGGG TGATCACAAT 5100
CGACTTGGTA TTGCCCTGCA AATCGGGTGT GTGCGTTTTC TGGGCACTTT TCTTACTGAC ATGAATCATA TTCCTTCCGG CGTCCGGCAT TTTACCGCCA 5200
GACAGCTCGG GATTCGTGAT ATCACCGTTC TTGCAGAATA CGGTCAGAGG GAAAATACCC GCCGTGAGCA TGCAGCGCTG ATACGTCAGC ACTATCAGTA 5300
TCGTGAATTT GCCTGGCCCT GGACATTTCG CCTTACCCGT CTTTTATATA CCCGGAGCTG GATAAGCAAC GAACGTCCTG GCCTGCTTTT CGACCTGGCG 5400
ACAGGGTGGC TTATGCAACA TCGTATTATT CTCCCCGGAG CCACCACGCT GACCCGGTTG ATTTCAGAGG TAAGGGAAAA GGCGACGTTG CGCCTGTGGA 5500
ACAAACTGGC ACTGATACCG TCAGCCGAAC AGCGTTCACA GCTGGAGATG CTGCTGGGGC CAACTGATTG CAGCCGCCTG TCTTTACTGG AATCACTGAA 5600
AAAAGGCCCT GTGACCATCA GTGGTCCGGC GTTTAATGAA GCAATTGAAC GCTGGAAAAC TCTGAACGAT TTTGGCCTGC ATGCTGAAAA CCTGAGTACA 5700
CTCCCGGCTG TGCGCCTGAA AAATCTCGCA CGTTATGCTG GTATGACTTC GGTGTTCAAT ATTGCCAGGA TGTCACCGCA GAAAAGGATG GCGGTTCTGG 5800
TTGCCTTTGT CCTTGCATGG GAAACGCTGG CGCTGGATGA TGCACTGGAC GTTCTGGACG CCATGCTGGC CGTTATCATC CGTGACGCCA GAAAGATTGG 5900
GCAGAAAAAA CGGCTCCGCT CGCTGAAGGA TCTGGATAAA TCTGCATTGG CGCTCGCCAG CGCATGTTCG TACTTGCTGA AAGAAGAAAC ACCGGACGAA 6000
TCGATTCGTG CTGAGGTGTT CAGCTACATC CCTAGGCAAA AGCTGGCTGA AATCATCACG CTTGTCCGTG AAATTGCCCG GCCCTCAGAC GATAATTTTC 6100
ATGACGAAAT GGTGGAGCAG TACGGGCGCG TTCGTCGTTT CCTGCCCCAT CTGCTGAATA CCGTTAAATT TTCATCCGCA CCTGCCGGGG TTACCACTCT 6200
GAATGCCTGT GACTACCTCA GCCGGGAGTT CAGCTCACGG CGGCAGTTTT TTGACGACGC ACCAACGGAA ATCATCAGTC AGTCATGGAA ACGGCTGGTG 6300
ATTAACAAGG AAAAACATAT CACCCGAAGG GGATACACGC TCTGCTTTCT CAGTAAACTG CAGGATAGTC TGAGACGGAG GGATGTCTAC GTTACCGGCA 6400
GTAACCGGTG GGGAGATCCT CGTGCAAGAT TACTACAGGG TGCTGACTGG CAGGCAAATC GGATTAAGGT TTATCGTTCT TTGGGGCACC CGACAGACCC 6500
GCAGGAAGCA ATAAAATCTC TGGGCCATCA GCTTGATAGT CGTTACAGAC AGGTTGCTGC ACGTCTTGGC GAAAATGAGG CTGTCGAACT CGATGTTTCT 6600
GGCCCGAAGC CCCGGTTGAC AATTTCTCCC CTCGCCAGTC TTGATGAGCC GGACAGTCTG AAACGACTGA GCAAAATGAT CAGTGATCTG CTCCCTCCGG 6700
TGGATTTAAC GGAGTTGCTG CTCGAAATTA ACGCCCATAC CGGATTTGCT GATGAGTTTT TCCATGCCAG TGAAGCCAGT GCCAGAGTTG ATGATCTGCC 6800
CGTCAGCATC AGCGCCGTGC TGATGGCTGA AGCCTGCAAT ATCGGTCTGG AACCACTGAT CAGATCAAAT GTTCCTGCAC TGACCCGACA CCGGCTGAAC 6900
TGGACAAAAG CGAACTATCT GCGGGCTGAA ACTATCACCA GCGCTAATGC CAGACTGGTT GATTTTCAGG CAACGCTGCC ACTGGCACAG ATATGGGGTG 7000
GAGGAGAAGT GGCATCTGCA GATGGAATGC GCTTTGTTAC GCCAGTCAGA ACAATCAATG CCGGACCGAA CCGCAAATAC TTTGGTAATA ACAGAGGGAT 7100
CACCTGGTAC AACTTTGTGT CCGATCAGTA TTCCGGCTTT CATGGCATCG TTATACCGGG GACGCTGAGG GACTCTATCT TTGTGCTGGA AGGCCTTCTG 7200
GAACAGGAGA CCGGGCTGAA TCCAACCGAA ATTATGACCG ATACGGCAGG TGCCAGCGAT CTTGTCTTTG GCCTTTTCTG GCTGCTGGGA TACCAGTTTT 7300
CTCCACGCCT GGCTGATGCC GGTGCTTCGG TTTTCTGGCG AATGGACCAT GATGCCGACT ATGGCGTGCT GAATGATATT GCCAGAGGGC AATCAGATCC 7400
CCGAAAAATA GTCCTTCAGT GGGACGAAAT GATCCGGACC GCAGGCTCCC TGAAGCTGGG CAAAGTACAG GCCTCAGTGC TGGTCCGTTC ATTGCTGAAA 7500
AGTGAACGTC CCTCCGGACT GACTCAGGCA ATCATTGAAG TGGGGCGCAT CAACAAAACG CTGTATCTGC TTAATTATAT TGATGATGAA GATTACCGCC 7600
GGCGCATTCT GACCCAGCTT AATCGGGGAG AAAGCCGTCA TGCAGTTGCC AGAGCCATCT GTCACGGTCA AAAAGGTGAG ATAAGAAAAC GATATACCGA 7700
CGGTCAGGAA GATCAGTTGG GAGCTCTGGG GCTGGTCACT AACGCCGTCG TGTTATGGAA CACTATTTAT ATGCAGGCAG CTCTGGATCA TCTCCGGGCG 7800
CAGGGTGAAA CACTGAATGA TGAAGATATC GCACGCCTCT CCCCGCTTTG CCACGGACAT ATCAATATGC TCGGCCATTA TTCCTTCACG CTGGCAGAAC 7900
TGGTGACCAA AGGACATCTG AGACCATTAA AAGAGGCGTC AGAGGCAGAA AACGTTGCTT AACGTGAGTT TTCGTTCCAC TGAGCGTCAG ACCCC

 Recombination Sites     

Name Coordinates Gene Sequence
attC bla OXA-9 core 1621-1689 69 CGTTCAAGGT GAGCGGACTC GCGCGGCTTT ATGCGCGAGG TCCGCTCGAG CGCAGGGTTA
TGCATCTGC
attC aadA core 2536-2590 55 GGTATCCTTC ATTGCTCCGC TGTGCGCTTA ATAGGTGCAT AACTTTGTTT TAGAC
attC AAC(6')-Ib core 3390-3455 66 CGTTTGACAT GAGGGGCGGC CAAGGGCGCC AGCCCTTGGA CGTCCCCCTC GATGGAAGGG
TTAGGC
res 4798-4918 121 AAATGTACCT TAAATCGAAT ATCAGACACG ATGTGTCTAT TATGCCAAAA TGACGATTTA
ATGGACACTC AAACGAAGCC GTTTTACTAT GTCTGATAAT TTATAATATT TCGAACGGTT
G
res_site_III 4801-4823 23 TGTACCTTAA ATCGAATATC AGA
res_site_II 4829-4864 36 TGTGTCTATT ATGCCAAAAT GACGATTTAA TGGACA
res_site_I 4887-4915 29 TGTCTGATAA TTTATAATAT TTCGAACGG

 ORFs     
ORF Summary
Gene Name Associated TE Coordinates Class Sub Class Orientation
bla TEM-1 (ARO:3000873) Tn6238 148-1008 Passenger Gene Antibiotic Resistance -
tnpR_p Tn6238 1191-1509 Accessory Gene Resolvase -
bla OXA-9 (ARO:3001404) Tn6238 1708-2547 Passenger Gene Antibiotic Resistance -
aadA (ARO:3002601) Tn6238 2592-3380 Passenger Gene Antibiotic Resistance -
AAC(6')-Ib10 (ARO:3002581) Tn6238 3450-4004 Passenger Gene Antibiotic Resistance -
tnpR Tn6238 4238-4795 Accessory Gene Resolvase -
tnpA Tn6238 4924-7962 Transposase   +

ORF Details
Gene Name Protein Name Associated TE Gene Length Coordinates Strand
bla TEM-1 (ARO:3000873) Bla TEM-1 Tn6238 861 148-1008 -
Class:   Passenger Gene
Sub Class:   Antibiotic Resistance
Function:   antibiotic inactivation (ARO:0001004)
Target:   penem (ARO:3003706)||cephalosporin (ARO:0000032)||monobactam (ARO:0000004)||penam (ARO:3000008)
Sequence Family:  TEM beta-lactamase (ARO:3000014)
Comment:   perfect match to reference sequence for ARO:3000873||Synonyms: TEM-98, RTEM-1
Protein Sequence:  
 MSIQHFRVAL IPFFAAFCLP VFAHPETLVK VKDAEDQLGA RVGYIELDLN SGKILESFRP EERFPMMSTF KVLLCGAVLS RVDAGQEQLG RRIHYSQNDL
VEYSPVTEKH LTDGMTVREL CSAAITMSDN TAANLLLTTI GGPKELTAFL HNMGDHVTRL DRWEPELNEA IPNDERDTTM PAAMATTLRK LLTGELLTLA
SRQQLIDWME ADKVAGPLLR SALPAGWFIA DKSGAGERGS RGIIAALGPD GKPSRIVVIY TTGSQATMDE RNRQIAEIGA SLIKHW

Gene Name Protein Name Associated TE Gene Length Coordinates Strand
tnpR_p TnpR_p Tn6238 319 1191-1509 -
Class:   Accessory Gene
Sub Class:   Resolvase
Transpoase Chemistry:   Serine
Sequence Family:  Serine Site-Specific Recombinase
Comment:   C-terminal fragment
Protein Sequence:  
 KRV*CSGCSG SVY*RRDQYR R*YGANGGHH PVGCGTG*TP EDPRAHE*GP TGSKAERNQI WPQAYRGQER RADASSEGHW CNGNCSSAQY CPLHGL*NS*
RRKGLV

Gene Name Protein Name Associated TE Gene Length Coordinates Strand
bla OXA-9 (ARO:3001404) Bla OXA-9 Tn6238 840 1708-2547 -
Class:   Passenger Gene
Sub Class:   Antibiotic Resistance
Function:   antibiotic inactivation (ARO:0001004)
Target:   cephalosporin (ARO:0000032)||penam (ARO:3000008)
Sequence Family:  OXA beta-lactamase (ARO:3000017)
Comment:   strict match to reference sequence for ARO:3001404 (bitscore: 569)
Protein Sequence:  
 MKDTLMKKIL LLHMLVFVSA TLPISSVASD EVETLKCTII ADAITGNTLY ETGECARRVS PCSSFKLPLA IMGFDSGILQ SPKSPTWELK PEYNPSPRDR
TYKQVYPALW QSDSVVWFSQ QLTSRLGVDR FTEYVKKFEY GNQDVSGDSG KHNGLTQSWL MSSLTISPKE QIQFLLRFVA HKLPVSEAAY DMAYATIPQY
QAAEGWAVHG KSGSGWLRDN NGKINESRPQ GWFVGWAEKN GRQVVFARLE IGKEKSDIPG GSKAREDILV ELPVLMGNK

Gene Name Protein Name Associated TE Gene Length Coordinates Strand
aadA (ARO:3002601) AadA Tn6238 789 2592-3380 -
Class:   Passenger Gene
Sub Class:   Antibiotic Resistance
Function:   antibiotic inactivation (ARO:0001004)
Target:   aminoglycoside antibiotic (ARO:0000016)
Sequence Family:  ANT(3'') (ARO:3004275)
Comment:   strict match to reference sequence for ARO:3002601 (bitscore: 520)||Synonym: ANT(9)(3'')
Protein Sequence:  
 MREAVIAEVS TQLSEVVGVI ERHLEPTLLA VHLYGSAVDG GLKPHSDIDL LVTVTVRLDE TTRRALINDL LETSASPGES EILRAVEVTI VVHDDIIPWR
YPAKRELQFG EWQRNDILAG IFEPATIDID LAILLTKARE HSVALVGPAA EELFDPVPEQ DLFEALNETL TLWNSPPDWA GDERNVVLTL SRIWYSAVTG
KIAPKDVAAD WAMERLPAQY QPVILEARQA YLGQEDRLAS RADQLEEFVH YVKGEITKVV GK

Gene Name Protein Name Associated TE Gene Length Coordinates Strand
AAC(6')-Ib10 (ARO:3002581) AAC(6')-Ib10 Tn6238 555 3450-4004 -
Class:   Passenger Gene
Sub Class:   Antibiotic Resistance
Function:   antibiotic inactivation (ARO:0001004)
Transpoase Chemistry:   aminoglycoside acetyltransferase
Target:   aminoglycoside antibiotic (ARO:0000016)
Sequence Family:  AAC(6') (ARO:3000345)
Comment:   strict match to reference sequence for ARO:3002581 (bitscore: 377)
Protein Sequence:  
 MTNSNDSVTL RLMTEHDLAM LYEWLNRSHI VEWWGGEEAR PTLADVQEQY LPSVLAQESV TPYIAMLNGE PIGYAQSYVA LGSGDGRWEE ETDPGVRGID
QLLANASQLG KGLGTKLVRA LVELLFNDPE VTKIQTDPSP SNLRAIRCYE KAGFERQGTV TTPYGPAVYM VQTRQAFERT RSVA

Gene Name Protein Name Associated TE Gene Length Coordinates Strand
tnpR TnpR Tn6238 558 4238-4795 -
Class:   Accessory Gene
Sub Class:   Resolvase
Function:   resolvase; serine site-specific recombinase
Transpoase Chemistry:   Serine
Sequence Family:  Serine Site-Specific Recombinase
Comment:   first defined as a repressor
Protein Sequence:  
 MRIFGYARVS TSQQSLDIQI RALKDAGVKA NRIFTDKASG SSTDREGLDL LRMKVEEGDV ILVKKLDRLG RDTADMIQLI KEFDAQGVAV RFIDDGISTD
GDMGQMVVTI LSAVAQAERR RILERTNEGR QEAKLKGIKF GRRRTVDRNV VLTLHQKGTG ATEIAHQLSI ARSTVYKILE DERAS

Gene Name Protein Name Associated TE Gene Length Coordinates Strand
tnpA TnpA Tn6238 3039 4924-7962 +
Class:   Transposase
Function:   transposase
Transpoase Chemistry:   DDE
Comment:   In frame three amino acid deletion relative to tnpA (Tn3)
Protein Sequence:  
 VLKKPSGREA DMPVDFLTTE QVESYGRFTG EPDELQLARY FHLDEADKEF IGKSRGDHNR LGIALQIGCV RFLGTFLTDM NHIPSGVRHF TARQLGIRDI
TVLAEYGQRE NTRREHAALI RQHYQYREFA WPWTFRLTRL LYTRSWISNE RPGLLFDLAT GWLMQHRIIL PGATTLTRLI SEVREKATLR LWNKLALIPS
AEQRSQLEML LGPTDCSRLS LLESLKKGPV TISGPAFNEA IERWKTLNDF GLHAENLSTL PAVRLKNLAR YAGMTSVFNI ARMSPQKRMA VLVAFVLAWE
TLALDDALDV LDAMLAVIIR DARKIGQKKR LRSLKDLDKS ALALASACSY LLKEETPDES IRAEVFSYIP RQKLAEIITL VREIARPSDD NFHDEMVEQY
GRVRRFLPHL LNTVKFSSAP AGVTTLNACD YLSREFSSRR QFFDDAPTEI ISQSWKRLVI NKEKHITRRG YTLCFLSKLQ DSLRRRDVYV TGSNRWGDPR
ARLLQGADWQ ANRIKVYRSL GHPTDPQEAI KSLGHQLDSR YRQVAARLGE NEAVELDVSG PKPRLTISPL ASLDEPDSLK RLSKMISDLL PPVDLTELLL
EINAHTGFAD EFFHASEASA RVDDLPVSIS AVLMAEACNI GLEPLIRSNV PALTRHRLNW TKANYLRAET ITSANARLVD FQATLPLAQI WGGGEVASAD
GMRFVTPVRT INAGPNRKYF GNNRGITWYN FVSDQYSGFH GIVIPGTLRD SIFVLEGLLE QETGLNPTEI MTDTAGASDL VFGLFWLLGY QFSPRLADAG
ASVFWRMDHD ADYGVLNDIA RGQSDPRKIV LQWDEMIRTA GSLKLGKVQA SVLVRSLLKS ERPSGLTQAI IEVGRINKTL YLLNYIDDED YRRRILTQLN
RGESRHAVAR AICHGQKGEI RKRYTDGQED QLGALGLVTN AVVLWNTIYM QAALDHLRAQ GETLNDEDIA RLSPLCHGHI NMLGHYSFTL AELVTKGHLR
PLKEASEAEN VA

 References     

Quiroga MP, Orman B, Errecalde L, Kaufman S, Centrón D. Characterization of Tn6238 with a new allele of aac(6')-Ib-cr. Antimicrob Agents Chemother. 2015 May;59(5):2893-7. doi: 10.1128/AAC.03213-14. Epub 2015 Feb 17. PubMed ID: 25691640