Difference between revisions of "Transposons families/Tn3 family"

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===Historical ===
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Members of the Tn''3'' family were among the earliest transposons to be identified. In fact, the word “transposon” was used for the first time [[General Information/IS History|in 1974 by Hedges and Jacob]] in a seminal article in which they showed that [[wikipedia:Ampicillin|ampicillin]] resistance could be transmitted between a number of different plasmids <ref name=":0"><pubmed>4609125</pubmed></ref>:    <blockquote>''“We designate DNA sequences with transposition potential as transposons (units of transposition) and the transposon marked by the ampicillin resistance gene(s) as transposon A “.''  </blockquote>

Revision as of 23:26, 29 April 2022

Historical

Members of the Tn3 family were among the earliest transposons to be identified. In fact, the word “transposon” was used for the first time in 1974 by Hedges and Jacob in a seminal article in which they showed that ampicillin resistance could be transmitted between a number of different plasmids [1]:

“We designate DNA sequences with transposition potential as transposons (units of transposition) and the transposon marked by the ampicillin resistance gene(s) as transposon A “.

  1. Hedges RW, Jacob AE . Transposition of ampicillin resistance from RP4 to other replicons. - Mol Gen Genet: 1974, 132(1);31-40 [PubMed:4609125] [DOI]