IS902
- Family IS110
- Group
Isoform IS901Synonym(s)
| Accession number | Transposition | Origin | Host |
|---|---|---|---|
| X58030 | ND | Mycobacterium avium | Mycobacterium avium subsp. silvaticum 0109 Mycobacterium avium subsp. silvaticum 0016 Mycobacterium avium subsp. silvaticum 0009 Mycobacterium avium subsp. silvaticum 0011 |
DNA section
IS Length : 1470 bp
Ends
Left end : TCCTTAGGGTTGAAGGGGTCTGGGATTGGATGTCCTGGATGCCCAGGACGGTGGGGTGTGGCTAATGTGTTGTTGCAACGGTTGTTGCTTGAAAGGAATG
Right end : GCTGCGCGACAACAGAACCTGGCAACCCCAGCAACCAACCGTGGCAGCTGCCTGACGCACTCACCGGGCGTCCTCACCGCTTGACACGCTCATTGAGATT
Insertion site
| Left flank | Direct repeat | Right flank | DR Length |
|---|---|---|---|
| ATGATCAATT | CCTTTCNNNN | 0 | |
| CATTTACAGT | CCTTTCNNNN | 0 |
DNA sequence
TCCTTAGGGTTGAAGGGGTCTGGGATTGGATGTCCTGGATGCCCAGGACGGTGGGGTGTGGCTAATGTGTTGTTGCAACGGTTGTTGCTTGAAAGGAATG
GCCGCCCTGCCGTTTTGGACGGTCCTGGCCACTGATTGAGATCTGACGCGTACTCGATGACGCTGCTCTAAGGACCTGTTGGCGGGGTTGTCCGCGGGGA
CTGCGACGACAGGAGTAGCGGTATGGCCGAACCCGACCGAGTGTGGGTGGGTATCGACGTCGGTAAGTCCACTCATCATGCGTGCGCGATCGATGACACC
GGAAAGGTGGTGTGGTCGAAGAAAATCCCGAACGAACAGGCCGCGATCGAAGACCTGATCGCCCAGGGCGGCCGGATTGCTAACCACGTGGTGTGGGCGA
TCGATTTGACCTCGCCGCCGGCGGCGCTGCTGATCGCCGTACTGCTGAGCGCGAAACGCGAGGTGGTGTATGTGCCGGGCCGCACGGTTAACACGATGAG
TCATGCGTTCCGCGGCGAAGGCAAGACCGACGCCAAAGACGCGCGGGTAATCGCCGAAACCGCTCGGCACCGACGAGATCTGTCCCCGGTCGTACCCGGC
GAAGACCTGGTTGCCGAATTGCGGTCGCTGACCCGATACCGGTCGGATCTGATGGCTGACTGGGTGCGAGGCGTGAACCGGCTGCGCTCGATGCTCACCG
CCATCTTCCCTGCTCTGGAAGCTGCGTTCGACTACTCCACCCGCGCGCCGTTGATCCTGGTATCCGCTATGTGCACTCCGGGCGAAATCCGGTCGGCAAA
AAGAGCTGGCGTGATCAAGCACCTTCGGAAAAACCGGGCATGGCCCAACAACATCGACACGATCGCCGACAAGGCGCTCGCCGCGGCAGCAGGCCAGATA
ATCACCCTTCCCGGCGAAGAAGCCGCCGCGCTCATCAAGCAACTCGCAGCACGGCTGCTGGACTTGGATCGGCAGATCAAGGACATCGATAAGCAAATCA
CCAACAAATTTGGTGAGCATCCCAGCGCCGCCATCATCGAGTCGATGCCCGGCATGGGGCCACACCTGGGCGCTGAGTTCCTCGTAATCACCGGCGGCAA
CATGGCCGCCTTCACCAACCCCGGCCGACTGGCATCGTTCGCCGGATTGGTACCCGTCCCACGCGATTCCGGCCGTATCACCGGCAATCTGCATCGGCCC
AAGCGCTACAACCGGCGCCTGCGCCGCGTGTTCTACCTCGCCGCCCTGTCCAGCCTCAAGATCGAAGGTTCCTCGCGGGCTTTCTACGACCGCAAACGAT
CCGAGAACCATATCCACACCCAGGCCCTGCTTGCCCTGGCACGCCGCCACGTCGACGTCCTGTGGGCACTGCTGCGCGACAACAGAACCTGGCAACCCCA
GCAACCAACCGTGGCAGCTGCCTGACGCACTCACCGGGCGTCCTCACCGCTTGACACGCTCATTGAGATT
GCCGCCCTGCCGTTTTGGACGGTCCTGGCCACTGATTGAGATCTGACGCGTACTCGATGACGCTGCTCTAAGGACCTGTTGGCGGGGTTGTCCGCGGGGA
CTGCGACGACAGGAGTAGCGGTATGGCCGAACCCGACCGAGTGTGGGTGGGTATCGACGTCGGTAAGTCCACTCATCATGCGTGCGCGATCGATGACACC
GGAAAGGTGGTGTGGTCGAAGAAAATCCCGAACGAACAGGCCGCGATCGAAGACCTGATCGCCCAGGGCGGCCGGATTGCTAACCACGTGGTGTGGGCGA
TCGATTTGACCTCGCCGCCGGCGGCGCTGCTGATCGCCGTACTGCTGAGCGCGAAACGCGAGGTGGTGTATGTGCCGGGCCGCACGGTTAACACGATGAG
TCATGCGTTCCGCGGCGAAGGCAAGACCGACGCCAAAGACGCGCGGGTAATCGCCGAAACCGCTCGGCACCGACGAGATCTGTCCCCGGTCGTACCCGGC
GAAGACCTGGTTGCCGAATTGCGGTCGCTGACCCGATACCGGTCGGATCTGATGGCTGACTGGGTGCGAGGCGTGAACCGGCTGCGCTCGATGCTCACCG
CCATCTTCCCTGCTCTGGAAGCTGCGTTCGACTACTCCACCCGCGCGCCGTTGATCCTGGTATCCGCTATGTGCACTCCGGGCGAAATCCGGTCGGCAAA
AAGAGCTGGCGTGATCAAGCACCTTCGGAAAAACCGGGCATGGCCCAACAACATCGACACGATCGCCGACAAGGCGCTCGCCGCGGCAGCAGGCCAGATA
ATCACCCTTCCCGGCGAAGAAGCCGCCGCGCTCATCAAGCAACTCGCAGCACGGCTGCTGGACTTGGATCGGCAGATCAAGGACATCGATAAGCAAATCA
CCAACAAATTTGGTGAGCATCCCAGCGCCGCCATCATCGAGTCGATGCCCGGCATGGGGCCACACCTGGGCGCTGAGTTCCTCGTAATCACCGGCGGCAA
CATGGCCGCCTTCACCAACCCCGGCCGACTGGCATCGTTCGCCGGATTGGTACCCGTCCCACGCGATTCCGGCCGTATCACCGGCAATCTGCATCGGCCC
AAGCGCTACAACCGGCGCCTGCGCCGCGTGTTCTACCTCGCCGCCCTGTCCAGCCTCAAGATCGAAGGTTCCTCGCGGGCTTTCTACGACCGCAAACGAT
CCGAGAACCATATCCACACCCAGGCCCTGCTTGCCCTGGCACGCCGCCACGTCGACGTCCTGTGGGCACTGCTGCGCGACAACAGAACCTGGCAACCCCA
GCAACCAACCGTGGCAGCTGCCTGACGCACTCACCGGGCGTCCTCACCGCTTGACACGCTCATTGAGATT
Protein section
ORF number : 1
ORF 1
| Length | Begin | End | Strand | Fusion ORF | |
|---|---|---|---|---|---|
| 1203 bp | 400 aa | 223 | 1425 | + | No |
Chemistry : DEDD
ORF sequence :
MAEPDRVWVGIDVGKSTHHACAIDDTGKVVWSKKIPNEQAAIEDLIAQGGRIANHVVWAIDLTSPPAALLIAVLLSAKREVVYVPGRTVNTMSHAFRGEG
KTDAKDARVIAETARHRRDLSPVVPGEDLVAELRSLTRYRSDLMADWVRGVNRLRSMLTAIFPALEAAFDYSTRAPLILVSAMCTPGEIRSAKRAGVIKH
LRKNRAWPNNIDTIADKALAAAAGQIITLPGEEAAALIKQLAARLLDLDRQIKDIDKQITNKFGEHPSAAIIESMPGMGPHLGAEFLVITGGNMAAFTNP
GRLASFAGLVPVPRDSGRITGNLHRPKRYNRRLRRVFYLAALSSLKIEGSSRAFYDRKRSENHIHTQALLALARRHVDVLWALLRDNRTWQPQQPTVAAA
KTDAKDARVIAETARHRRDLSPVVPGEDLVAELRSLTRYRSDLMADWVRGVNRLRSMLTAIFPALEAAFDYSTRAPLILVSAMCTPGEIRSAKRAGVIKH
LRKNRAWPNNIDTIADKALAAAAGQIITLPGEEAAALIKQLAARLLDLDRQIKDIDKQITNKFGEHPSAAIIESMPGMGPHLGAEFLVITGGNMAAFTNP
GRLASFAGLVPVPRDSGRITGNLHRPKRYNRRLRRVFYLAALSSLKIEGSSRAFYDRKRSENHIHTQALLALARRHVDVLWALLRDNRTWQPQQPTVAAA
Blast result :
Comments
Mycobacterium avium subsp. silvaticum is thought to be involved in Crohn's disease, a human enteritis. IS902 shows 99 % DNA homology to IS901. IS902 ORF shares 50 % identity with those of IS900 and IS116, and 35 % with IS110 ORF.
References
1] Moss, M.T., Malik, Z.P., Tizard, M.L.V., Green, E.P., Sanderson, J.D. and Hermon-Taylor, J. (1992) J. Gen. Microbiol. 138, 139-145.
2] Doran, T.J., Davies, J.K., Radford, A.J., and Hodgson, A.L.M. (1994) Imm. Cell Biol. 72, 427-434.
2] Doran, T.J., Davies, J.K., Radford, A.J., and Hodgson, A.L.M. (1994) Imm. Cell Biol. 72, 427-434.