IS901
- Family IS110
- Group
Isoform Synonym(s)
| Accession number | Transposition | Origin | Host |
|---|---|---|---|
| X59272 | ND | Mycobacterium avium | Mycobacterium paratuberculosis 18 Mycobacterium avium FP8589 Mycobacterium avium ATCC2103 Mycobacterium avium ATCC19421 |
DNA section
IS Length : 1472 bp
Ends
Left end : TTCCTTAGGGTTGAAGGGGTCTGGGATTGGATGTCCTGGATGCCCAGGACGGTGGGGTGTGGCTAATGTGTTGTTGCAACGGTTGTTGCTTGAAAGGAAT
Right end : CTGCTGCGCGACAACAGAACATGGCAACCCCAGCAACCAACCGTGGCAGCTGCCTGACGCACTCACCGGGCGTCCTCACCGCTTGACACGCTCATTGAGA
Insertion site
| Left flank | Direct repeat | Right flank | DR Length |
|---|---|---|---|
| CATGCGCTGA | TTCCTTTCAG | 0 | |
| CATTGGTGGC | TTCCGTTCGG | 0 |
DNA sequence
TTCCTTAGGGTTGAAGGGGTCTGGGATTGGATGTCCTGGATGCCCAGGACGGTGGGGTGTGGCTAATGTGTTGTTGCAACGGTTGTTGCTTGAAAGGAAT
GGCCGCCCTGCCGTTTTGGACGGTCCTGGCCACTGATTGAGATCTGACGCGTACTCGATGACGCTGCTCTAAGGACCTGTTGGCGGGGTTGTCCGCGGGG
ACTGCGACGACAGGAGTAGCGGTATGGCCGAACCCGACCGAGTGTGGGTGGGTATCGACGTCGGTAAGTCCACTCATCATGCGTGCGCGATCGATGACAC
CGGAAAGGTGGTGTGGTCGAAGAAAATCCCGAACGAACAGGCCGCGATCGAAGACCTGATCGCCCAGGGCGGCCGGATTGCTAACCACGTGGTGTGGGCG
ATCGATTTGACCTCGCGCCGGCGGCGGCTGCTGATCGCCGTACTGCTGAGCGCGAAAGCCGAGGTGGTGTATGTGCCGGGCCGCACGGTTAACACGATGA
GTCATGCGTTCCGCGGCGAAGGCAAGACCGACGCCAAAGACGCGCGGGTAATCGCCGAAACCGCTCGGCACCGACGAGATCTGTCCCCGGTCGTACCCGG
CGAAGACCTGGTTGCCGAATTGCGGTCGCTGACCGCATACCGGTCGGATCTGATGGCTGACTGGGTGCGAGGCGTGAACCGCGTGCGCTCGATGCTCACC
GCCATCTTCCCTGCTCTGGAAGCTGCGTTCGACTACTCCACCCGCGCGCCGTTGATCCTGGTATCCGCTATGTGCACTCCGGGCGAAATCCGGTCGGCAA
AAAGAGCTGGCGTGATCAAGCACCTTCGGAAAAACCGGGCATGGCCCAACAACATCGACACGATCGCCGACAAGGGCCTCGCCGCGGCAGCAGGCCAGAT
AATCACCCTTCCCGGCGAAGCCGGAACCGCCGCGCTCATCAAGCAACTCGCAGCACGGCTGCTGGACTTGGATCGGCAGATCAAGGACATCGATAAGCAA
ATCACCAACAAATTTCGTGAGCATCCCAGCGCCGCCATCATCGAGTCGATGCCCGGCATGGGGCCACACCTGGGCGCTGAGTTCCTCGTAATCACCGGCG
GCAACATGGCCGCCTTCACCAACCCCGGCCGACTGGCATCGTTCGCCGGATTGGTACCCGTCCCACGCGATTCCGGCCGTATCACCGGCAATCTGCATCG
GCCCAAGCGCTACAACCGGCGCCTGCGCCGCGTGTTCTACCTCGCCGCCCTGTCCAGCCTCAAGATCGAAGGTCCCTCGCGGGCTTTCTACGACCGCAAA
CGATCCGAGAACCATATCCACACCCAGGCCCTGCTTGCCCTGGCACGCCGCCACGTCGACGTCCTGTGGGCACTGCTGCGCGACAACAGAACATGGCAAC
CCCAGCAACCAACCGTGGCAGCTGCCTGACGCACTCACCGGGCGTCCTCACCGCTTGACACGCTCATTGAGA
GGCCGCCCTGCCGTTTTGGACGGTCCTGGCCACTGATTGAGATCTGACGCGTACTCGATGACGCTGCTCTAAGGACCTGTTGGCGGGGTTGTCCGCGGGG
ACTGCGACGACAGGAGTAGCGGTATGGCCGAACCCGACCGAGTGTGGGTGGGTATCGACGTCGGTAAGTCCACTCATCATGCGTGCGCGATCGATGACAC
CGGAAAGGTGGTGTGGTCGAAGAAAATCCCGAACGAACAGGCCGCGATCGAAGACCTGATCGCCCAGGGCGGCCGGATTGCTAACCACGTGGTGTGGGCG
ATCGATTTGACCTCGCGCCGGCGGCGGCTGCTGATCGCCGTACTGCTGAGCGCGAAAGCCGAGGTGGTGTATGTGCCGGGCCGCACGGTTAACACGATGA
GTCATGCGTTCCGCGGCGAAGGCAAGACCGACGCCAAAGACGCGCGGGTAATCGCCGAAACCGCTCGGCACCGACGAGATCTGTCCCCGGTCGTACCCGG
CGAAGACCTGGTTGCCGAATTGCGGTCGCTGACCGCATACCGGTCGGATCTGATGGCTGACTGGGTGCGAGGCGTGAACCGCGTGCGCTCGATGCTCACC
GCCATCTTCCCTGCTCTGGAAGCTGCGTTCGACTACTCCACCCGCGCGCCGTTGATCCTGGTATCCGCTATGTGCACTCCGGGCGAAATCCGGTCGGCAA
AAAGAGCTGGCGTGATCAAGCACCTTCGGAAAAACCGGGCATGGCCCAACAACATCGACACGATCGCCGACAAGGGCCTCGCCGCGGCAGCAGGCCAGAT
AATCACCCTTCCCGGCGAAGCCGGAACCGCCGCGCTCATCAAGCAACTCGCAGCACGGCTGCTGGACTTGGATCGGCAGATCAAGGACATCGATAAGCAA
ATCACCAACAAATTTCGTGAGCATCCCAGCGCCGCCATCATCGAGTCGATGCCCGGCATGGGGCCACACCTGGGCGCTGAGTTCCTCGTAATCACCGGCG
GCAACATGGCCGCCTTCACCAACCCCGGCCGACTGGCATCGTTCGCCGGATTGGTACCCGTCCCACGCGATTCCGGCCGTATCACCGGCAATCTGCATCG
GCCCAAGCGCTACAACCGGCGCCTGCGCCGCGTGTTCTACCTCGCCGCCCTGTCCAGCCTCAAGATCGAAGGTCCCTCGCGGGCTTTCTACGACCGCAAA
CGATCCGAGAACCATATCCACACCCAGGCCCTGCTTGCCCTGGCACGCCGCCACGTCGACGTCCTGTGGGCACTGCTGCGCGACAACAGAACATGGCAAC
CCCAGCAACCAACCGTGGCAGCTGCCTGACGCACTCACCGGGCGTCCTCACCGCTTGACACGCTCATTGAGA
Protein section
ORF number : 1
ORF 1
| Length | Begin | End | Strand | Fusion ORF | |
|---|---|---|---|---|---|
| 1206 bp | 401 aa | 224 | 1429 | + | No |
Chemistry : DEDD
ORF sequence :
MAEPDRVWVGIDVGKSTHHACAIDDTGKVVWSKKIPNEQAAIEDLIAQGGRIANHVVWAIDLTSRRRRLLIAVLLSAKAEVVYVPGRTVNTMSHAFRGEG
KTDAKDARVIAETARHRRDLSPVVPGEDLVAELRSLTAYRSDLMADWVRGVNRVRSMLTAIFPALEAAFDYSTRAPLILVSAMCTPGEIRSAKRAGVIKH
LRKNRAWPNNIDTIADKGLAAAAGQIITLPGEAGTAALIKQLAARLLDLDRQIKDIDKQITNKFREHPSAAIIESMPGMGPHLGAEFLVITGGNMAAFTN
PGRLASFAGLVPVPRDSGRITGNLHRPKRYNRRLRRVFYLAALSSLKIEGPSRAFYDRKRSENHIHTQALLALARRHVDVLWALLRDNRTWQPQQPTVAA
A
KTDAKDARVIAETARHRRDLSPVVPGEDLVAELRSLTAYRSDLMADWVRGVNRVRSMLTAIFPALEAAFDYSTRAPLILVSAMCTPGEIRSAKRAGVIKH
LRKNRAWPNNIDTIADKGLAAAAGQIITLPGEAGTAALIKQLAARLLDLDRQIKDIDKQITNKFREHPSAAIIESMPGMGPHLGAEFLVITGGNMAAFTN
PGRLASFAGLVPVPRDSGRITGNLHRPKRYNRRLRRVFYLAALSSLKIEGPSRAFYDRKRSENHIHTQALLALARRHVDVLWALLRDNRTWQPQQPTVAA
A
Blast result :
Comments
The IS901 transposase sequence homologies with the other IS110 family members are: IS492 (18 %), IS1000 (23 %), IS117 (27 %), IS110 (32 %), IS900 (49 %), and IS116 (50 %) (Kunze et al., 1991). IS901 shows 99 % DNA identity to IS902.
References
1] Kunze, Z.M., Wall, S., Appelberg, R., Silva, M.T., Portaels, F., and McFadden, J.J. (1991) Mol. Microbiol. 5, 2265-2272.
2] Kunze, Z.M., Portaels, F., and McFadden, J.J. (1992) J. Clin. Microbiol. 30, 2366- 2372.
2] Kunze, Z.M., Portaels, F., and McFadden, J.J. (1992) J. Clin. Microbiol. 30, 2366- 2372.