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Terminal Inverted Repeats | |
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Recombination Sites | |
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Internal Transposable Elements | |
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Internal Repeats | |
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| Name: Tn6260 |
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| Family: Tn554 |
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| Evidence of Transposition: no |
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| Host |
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| Host Organism: | Listeria monocytogenes 6179 | Molecular Source: | chromosome |
| | Date of Isolation: | 2013 |
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| Map |
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| Sequence |
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--------10 --------20 --------30 --------40 --------50 --------60 --------70 --------80 --------90 -------100
TTATCCATAG TATAATGAAT AATAGTAGTT AAAGTAGTTT AGGAGGGGGA TATTAGGGAG GTTTTTACTT TAAATAAAAA TTAACAAGGT CTATAATTTA 100
TAGTAGTTAA AGTGGTTAAA GAGAGGTGGG AGGATGTGAA GGTTCAAAGG ATAAAAGTGG AGAATAAGCC ATATCCATTG TATTTATTGC TAGATGAAGA 200
ATATCAGGTA ATAGAACCAG TAATGAGGTT TATAAAATAT CTAGATAATA CTGGTAAGTC ACCAAATACC ATTAAAGCAT ACTGCTATCA TTTAAAGTTG 300
CTATATGAGT TTATGGAACA GAGGGGGATT ACCCTTAATG ATATTAACTT TGAGAAATTA GCAGATTTTG TAGGTTGGTT GAGATACCCA ACAGCAGCAA 400
ATGTAATTGA TCTCCAGTCA AAAGAAGCCA TAAGAGAAGA AACGACAGTG AATACAATTT TAAATGCTGT TATGAGTTAT CTGGAATATT TAAGTAGATT 500
AGGAGAATTT AAGTCAATTG ATGTATTTAA ACAAGCAAAG GGGAGAAATT TTAAGGGGTT TTTACATCAT ATTAATAAGG GTAAATATCA AAAGAATATC 600
TTAAAGTTAA GGGTTAAAAA GAAGCAGATA AGAACACTAA CATCAGAGGA AGTTAAGCAA ATTATTGATG CTTGTCATAC GAAGAGGGAT AAATTAATTT 700
TAATGCTTAT GTATGAGGGT GGTTTAAGAA TCGGTGAAGT GTTATCGCTA AGGCTTGAGG ATATTGCCAC TTGGGACAAT CAAATCCATT TAACACCCAG 800
AGACGTTAAT GTTAATGAGG CCTATATTAA ATTAAGGAAG GAAAGAACAA TACATGTGAG TAAAGAACTT ATGGCACTTT ATACAGATTA TTTGGTATAT 900
GAGTATGGTG AGGACTTGGA GCATGATTAT GTTTTTATTT CTTTAAAAGA AGGCTATTTT GGAAAACCAC TAAAGTACCA AAGTGTTCTT GATCTAGTTA 1000
GAAGAATAGT TAAAAGAACT AGAATAGAGT TTACGCCGCA TATGCTACGC CACACTCATG CAACGCAGCT AATTAGGGAT GGATGGGATG TTGCACACGT 1100
TCAAAAGAGG TTGGGCCATG CACATGTTCA AACAACGTTA AATACCTATG TTCATCTTTC AGATCAAGAT ATGAAAAATG AGTTTAATAA ATATCTTGAG 1200
AGAAAGGAAC ATAAGAAATG AATGATTCTA GTAAAAGGAA AATTATCAGT CAGAGTGAGA TCAGTAAGAA AATAGCTGCA ATGAATGAAG AATTGCAGGG 1300
ATTTTGGGCT AATAATAGTT GGGATATAAG GAAATGTCCG CATCCTTCTG CCATAGAATT AAGTAAGAAC CCTACTTTAA GAAATCGGTG GGTTCGTTTT 1400
GAACGTGTTA AAAATCTGTG GTTAAGAACA GAATTGAAAT ATTTTTATTT TTACCATTTA AATAATGGAA TATGGAATGC AAAAACTGTA TGGATTAGAA 1500
AAGGAACTGT AATTAATAGA ATGTTAGATT TTTTAGATTT AAAGTATCCT AACATTACTT CAATTACTGA AGTTCCTATT AAAAAAGCAA TGACGGAATA 1600
TAGGACATAT TTGACAGAAC AGGGTGTTAG AATTACCACT ACTAATTATA AGATTACTGC TAATCAAGAA AAAATAGCTG TAGAAGCTAA TTCTTACTAT 1700
GTTACTAATT TAAAACAATT TATGGAGTTT TATGAGGACT TTTATTTTGA TGGGGAGGAG TGGGATAAAG ACATTTGGGA TAGACGTAAG TTACCTTTGC 1800
CAGATGATAA GGTTAATCCG ACACAATATG AATATGTAAT TAACTTTAAA GGGGTTCGCA ATACGTATTT TAAACAACTC GTAAAAAGAT ATTGTAAATT 1900
GAGATTAAAT ACGGATAGCT TTTCCTATGT ATGTGATATC GCCCAAAAAC TTAAAGAGTT CTTTAATTTC TTGGACATGA ATTTTAAACA CGTTCAGAGA 2000
ATAAACCAAT TAACGAGAAT GGAAATTGAA GCATATTTAA GCGAATTAAA TATGATGGGG ATAAAGCCTA GCACAATAAC TGGGAGGATC TCTATATTGG 2100
AAGGACTATT TAGTACCCTT CTAAGGCTAG AATGGAATGA TATTCCTTCC AAGGTGTTAA TCTATCCAGA AGACTATCCC AAAATACCGA GAGCAAAACC 2200
TCGTTTTATA GATGAATACG TTCTGGAGCA ATTGAACAGT CATCTTGATA AATTACCCGA ATATATAGCT ACGATGACTA TGATAGTCCA AGAATGTGGG 2300
ATGAGGATAA GCGAATTGTG CACCTTGAAA AAAGGTTGTC TATTAGAGGA CAAAGATGGA GATTACTTTT TAAAGTATTA TCAATGGAAA ATGAAAAAGG 2400
AGCATATAGT TCCAATATCA AAAGAGGTAG CTTTATTGAT TAAAGTTCGG GAAGATAAAG TTTCATGGGA GTTTCCAGAT AGTGAATACC TCTTTCCAAG 2500
AAAAGATGGA TCGCCATTAA AACAAGAAAC ATTTAGAGAC GAGTTAAACA AATTAGCTTA TGAGCAAAAA ATAGTCGATA AATCAGGCGA GATTTATAGA 2600
TTCCATGCCC ATGCCTTTCG CCATACAGTA GGAACAAGAA TGATTAATAA CGGAGTACCG CAGCATATTG TACAAAAGTT TTTGGGTCAT GAAAGTCCTG 2700
AAATGACAAG CAGATATGCT CATATTTTTG ATGAAACCCT TAAAGCTGAA TTTACAAAAT TCAAAGAAAA ACTGGTAACT AATAATGGAG ATATAATTGA 2800
GTTAGATAAT GACAATGAAG TCGATGATGT TGATCTTCAA TGGTTCAAGA AAAATATTAA TGCACAAGTT CTTCCAAATG GTTATTGCCG ATTACCAGTA 2900
ATAGCAGGTT CTTGTCCACA CGCCAATGCT TGTTTAGATT GTACTCATTT TTGTACAAGT AAGCAGTTTT TATCGCAGCA TGAGGAACAG TTAAATCGTA 3000
CTGAGGAGTT ATTGGCAGTC GCTAAGGAAA AGCAATGGCA AAGGCAAATA GAGACTAATA ACCGTGTTAA AGAGCGACTA GAGCAAATAA TTGGCAGCCT 3100
GAAGGGGATT AGTTAGATGG TTAAACAGGT AAGAAATACA GAGGAAATTG TGCGTTTGGC AAAGCAAAAG TCCAGGCGGA CTAGAGAAAA TGTAGACAAG 3200
GTTATCTCTA AACTATCGCT TGAAGGTAAG ACTATTAATT TTAACACAGT TGCAAAGGAA GCTAATGTTT CTAAATCATG GCTTTATAAG GAACATGATA 3300
TTAGGCAAAG GATTGAATCT CTCCGAAAAC AGCAAAAAAC AGAAAATGTA ATATCAAAAC CCAAGAAAAG CTCCCGTTCT GAAGAAGTCC TTATTAAAAC 3400
CTTAAAAACA AGAGTAAAGG AATTAGAAGA GGAAAATATA AGATTAAGGA ACCAGATCCA AAAATTATAC GGAGATTTGT ACATTAGAGA ATAGTTAATC 3500
TATGAGTTTC ACCAACTTGT GCTTTGAACT TTGAAGTGTT AAAATTAATA TACTATTAAT CGAAAGGAGA GATGGGTGGA CAATGAAGAA CTAATCTAAT 3600
TTTTAACAAA TGAAATAGTA TATTTCAGTT TAAAAACTTA GGATTAGTCT GCCCATTTTT CCATATACTA AATAAATGTA AGACTGAATA GCTAAAAAGG 3700
CTAAATAGTT TTATTTGAGT CCTTAAAAAG TGACATGACT AATCCTTCCA ACATTATTTG GGAGGATTTT TTATTTCTCC CTGAATCAAA ATAAAGAAAG 3800
AAGGAATCGA ATTGTTAAAA CAAAAGGAAC TAATGGCAAG GGTTAAGGAA CTTGTCCAGT CAGATGAACG AATATCTGCT TGTATGATGT ATGGCTCTTT 3900
TACAAAAGGA GAGGGAGATC AATACTCTGA TATAGAATAT TACGTTTTTC TAAAAGATGA TACAATTTCC ACCTTTGATT CAGCAAAATG GCTAAATGAA 4000
GTCGCTTCCT ACACTTTACT CTATCAAAAT GAGTACGGTA CGGAAGTAGT AATTTTTGAA AATCTAATAC GTGGTGAATT TCATTTCCTT TCCGAAAACG 4100
AAATGAATAT TATTCCTTCA TTCAAAGAAT CAGGCTACAT TCCTGACACA AAAGCAATGT TTATTTATGA TGAAACAGGA CAACTAGAAT TGTATTTATC 4200
AGAGTTGGAA GGTCCGGGAC CAAATAGACT TACAGAAGAA AACGTAAATT TTTTATTGAA TAATTTTTCC AACCTATGGT TAATGGGGAT TAATGTTCTT 4300
AAAAGAGGGG AAAATGCACG TTCACTGGAA CTTTTATCTC AATTACAAAA AAATATACTA CAACTCATTC GAATTGCGGA AGAAAATGCC GATAATTGGT 4400
TTAATATGAC AAAGAATCTT GAAAAAGAAA TTAGTCCTGA AAACTATGAA AAGTTTAAAA AGACTACTGC CCGATTAAAT GAATTAGAAC TATATGAAGC 4500
CTATAAGAAC TCTTTGCTTC TCGTTATGGA ACTTCGAAAT CTCGTTGAAA AACAGTATCA ATTAACCATT AGCGATGATT TTTTAGGCAA ACTGTTTAAT 4600
TATATGAACG AATAAATAAA AAGCCTGTAT CTCAAGTGAT AACTAAGATA CAGGCTTTAA TTGTTATTTA CTTTAAATAC ATGTTCTCAA AGTGAAAGTA 4700
TTGATTTTAA TGGATTTTTA ATAGTTTACT CTTGATAA
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| ORFs |
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| Gene Name |
Associated TE |
Coordinates |
Class |
Sub Class |
Orientation |
| tnpA |
Tn6260 |
136-1221 |
Transposase |
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+ |
| tnpB |
Tn6260 |
1218-3116 |
Transposase |
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+ |
| tnpC |
Tn6260 |
3117-3494 |
Accessory Gene |
Helper |
+ |
| lnuG (ARO:3004085) |
Tn6260 |
3812-4615 |
Passenger Gene |
Antibiotic Resistance |
+ |
| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| tnpA |
TnpA |
Tn6260 |
1086 |
136-1221 |
+ |
| Class: | Transposase |
Protein Sequence:
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MKVQRIKVEN KPYPLYLLLD EEYQVIEPVM RFIKYLDNTG KSPNTIKAYC YHLKLLYEFM EQRGITLNDI NFEKLADFVG WLRYPTAANV IDLQSKEAIR
EETTVNTILN AVMSYLEYLS RLGEFKSIDV FKQAKGRNFK GFLHHINKGK YQKNILKLRV KKKQIRTLTS EEVKQIIDAC HTKRDKLILM LMYEGGLRIG
EVLSLRLEDI ATWDNQIHLT PRDVNVNEAY IKLRKERTIH VSKELMALYT DYLVYEYGED LEHDYVFISL KEGYFGKPLK YQSVLDLVRR IVKRTRIEFT
PHMLRHTHAT QLIRDGWDVA HVQKRLGHAH VQTTLNTYVH LSDQDMKNEF NKYLERKEHK K
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| tnpB |
TnpB |
Tn6260 |
1899 |
1218-3116 |
+ |
| Class: | Transposase |
Protein Sequence:
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MNDSSKRKII SQSEISKKIA AMNEELQGFW ANNSWDIRKC PHPSAIELSK NPTLRNRWVR FERVKNLWLR TELKYFYFYH LNNGIWNAKT VWIRKGTVIN
RMLDFLDLKY PNITSITEVP IKKAMTEYRT YLTEQGVRIT TTNYKITANQ EKIAVEANSY YVTNLKQFME FYEDFYFDGE EWDKDIWDRR KLPLPDDKVN
PTQYEYVINF KGVRNTYFKQ LVKRYCKLRL NTDSFSYVCD IAQKLKEFFN FLDMNFKHVQ RINQLTRMEI EAYLSELNMM GIKPSTITGR ISILEGLFST
LLRLEWNDIP SKVLIYPEDY PKIPRAKPRF IDEYVLEQLN SHLDKLPEYI ATMTMIVQEC GMRISELCTL KKGCLLEDKD GDYFLKYYQW KMKKEHIVPI
SKEVALLIKV REDKVSWEFP DSEYLFPRKD GSPLKQETFR DELNKLAYEQ KIVDKSGEIY RFHAHAFRHT VGTRMINNGV PQHIVQKFLG HESPEMTSRY
AHIFDETLKA EFTKFKEKLV TNNGDIIELD NDNEVDDVDL QWFKKNINAQ VLPNGYCRLP VIAGSCPHAN ACLDCTHFCT SKQFLSQHEE QLNRTEELLA
VAKEKQWQRQ IETNNRVKER LEQIIGSLKG IS
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| tnpC |
TnpC |
Tn6260 |
378 |
3117-3494 |
+ |
| Class: | Accessory Gene |
| Sub Class: | Helper |
| Sequence Family: | Tn554_family |
| Comment: | target specificity and orientation |
Protein Sequence:
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MVKQVRNTEE IVRLAKQKSR RTRENVDKVI SKLSLEGKTI NFNTVAKEAN VSKSWLYKEH DIRQRIESLR KQQKTENVIS KPKKSSRSEE VLIKTLKTRV
KELEEENIRL RNQIQKLYGD LYIRE
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| lnuG (ARO:3004085) |
LnuG |
Tn6260 |
804 |
3812-4615 |
+ |
| Class: | Passenger Gene |
| Sub Class: | Antibiotic Resistance |
| Function: | antibiotic inactivation (ARO:0001004) |
| Target: | lincosamide antibiotic (ARO:0000017) |
| Sequence Family: | lincosamide nucleotidyltransferase (LNU) (ARO:3000221) |
| Comment: | perfect match to reference sequence for ARO:3004085 (Bitscore 538) |
Protein Sequence:
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MLKQKELMAR VKELVQSDER ISACMMYGSF TKGEGDQYSD IEYYVFLKDD TISTFDSAKW LNEVASYTLL YQNEYGTEVV IFENLIRGEF HFLSENEMNI
IPSFKESGYI PDTKAMFIYD ETGQLELYLS ELEGPGPNRL TEENVNFLLN NFSNLWLMGI NVLKRGENAR SLELLSQLQK NILQLIRIAE ENADNWFNMT
KNLEKEISPE NYEKFKKTTA RLNELELYEA YKNSLLLVME LRNLVEKQYQ LTISDDFLGK LFNYMNE
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| References |
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Zhu XQ, Wang XM, Li H, Shang YH, Pan YS, Wu CM, Wang Y, Du XD, Shen JZ. Novel lnu(G) gene conferring resistance to lincomycin by nucleotidylation, located on Tn6260 from Enterococcus faecalis E531. J Antimicrob Chemother. 2017 Apr 1;72(4):993-997. doi: 10.1093/jac/dkw549. PubMed ID: 28039271
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