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Terminal Inverted Repeats | |
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Recombination Sites | |
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Internal Transposable Elements | |
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Internal Repeats | |
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| Name: Tn6188 |
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| Family: Tn554 |
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| Evidence of Transposition: Yes |
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| Host |
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| Host Organism: | Listeria monocytogenes 6179 | Molecular Source: | chromosome |
| Place of Origin: | Vienna, Austria | Date of Isolation: | 2013 |
| | Other Geographic Information: | University of Veterinary Medicine |
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| Map |
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| Sequence |
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--------10 --------20 --------30 --------40 --------50 --------60 --------70 --------80 --------90 -------100
TTAAACATAG TATCCTAAAC TAGAGTACTC TAAGTACTCA AAGTTTAGGA TTTTTTAATT ACAGTGCTTT AACTATTAAA TATATAAGGG TATTGTTAAT 100
AGTAGTTAAA GTATTTAAAG GTGGTGGAAA GATGAAAGTT CAGAAAGTAA TTGTGGAGGA AAAACCATAT CCGTTATACA TACTCCTAGA TAAAGAATTT 200
GAAGTGATAG AACCGGTTAA GAGATTTATA AAGTACTTGG ATAATACGGG CAAAGCTCCA AATACCATTA AAACATATTG TTATCATCTC AAATTGTTTT 300
ATGAATTTAT GAGCCAGAGA GGAATTGGAT TAGAAGATTT AAAATTCGAA GAAATGTCAA ACTTTGTTGG ATGGTTAAGA AATCCAACGG GGGATGTAAA 400
GGTAATAACT TTACAACCAA AGAAGGCTAA AAGAGAAGAA ACATCTGTTA ATGCCATACT TAATGCTATA ACTAGTTTTT TAGAGTATTT GAATCGCACA 500
GAAGATTTTA AAGCTATAGA CATGACTAAA GAAGCAAGGG GAAGAAATTT CAAGGGGTTT CTTCACCATA TCTCTAAAGG AAAATCTTAT AAAAAAAATA 600
TTTTAAAGCT TAGGGTTAAA AAGAAACTTG TGCAAGTTTT AGAACACGAA CAAGTTAAAG CAATAATTGA TGCGTGTCAT ACAAAAAGAG ATAAGTTACT 700
TATTATGCTT ATGTATGAAG GAGGACTTCG CATAGGAGAG GTATTATCCC TTCGTATCGA AGATATTTCT ACTTGGGATA ATCTGATTAA TATCACACCA 800
AGAGATCATA ATGAAAACGG GGCTTATATT AAGCTTAGAA AAGAACGAAC AATTGATGTT AGTAAGGAAT TAATGGCTTT ATATACCGAT TATTTAGTTC 900
ATGAATATGG AGAAGATTTA GAGCATGATT ATATATTTAT AAATCTCAAA GAATCTTATT TTGGGAAACC TCTAAAATAT CAAAGTGTAT TAGACCTTAT 1000
AAGGCGATTG GGAAAACGGA CAGGGATTAC CTTCACTGCC CACATGTTAC GTCATACGCA TGCTACAGAA CTCATTAGAA GTGGATGGGA TGCTGCTTAT 1100
GTACAAAAAA GGTTAGGTCA TGCACATGTA CAAACAACAC TTGATACGTA CGTTCATCTT TCTGATCAGG ACATGAAAAA TGAATATAAG GCGTATCTCC 1200
AAGGGAGAGA AACATAAAAA TGAAATTTCC GAGCGTTGCA ACTAATAGAA AACTTGTCAC TAGCACAGAG ATTAATAAAA AAATATCGGA TATGACTAGT 1300
GTTTTACAAG GGTTTTGGGC AGCAGATAGA TGGGATATAA GAATTTGTCC ACATCCTAGT GCGATTGAGT TAAGTAAGAA TCCATCATTA AAAAATCGTT 1400
GGGTAAATTT TGATAAAGTA GAAAACATCT GGTTAAAAAC AGAATTAAAA TACTTTTATT ATGTTCACTT AAATAATGGA ACATGGAATG CAAAATCTGT 1500
TTGGATTAGA AAAGGAACAG TGATAAGCCG AATGTTAGGA TTTTTAAATT TAAATTATCC CGATATTACA TCTATAACTG AAGTGCCTAT AAAAAAGGCT 1600
TTGTCGGAAT ATCGAACTTA CTTAGCAGAA CAAGGAATAA GAACTACGAC TACAAATTAC AAGCTTGATA TAAATCAAAA AAAAATTCCT GTATATGCGA 1700
ACTCCTACTA CGTTACTAAT CTTAAACAGT TTATGGAGTT CTATGAGGAT TTCTATTTTG ACGGCGATGA ATGGGAGAAA GATGTTTGGA ATCGAAGAAA 1800
ACTTTCACTA TCGGAAGATA AAGTAAATCC AACATCCTAT GAATACACAA TCAATTTCAA GGGGTTTGAA AATGATTATT TTAAAGAGTT AGTTAAACGA 1900
TATTGTAAGT TAATGTTAAA TACACGCAGC TTTTCCCATG TTGTTGATAC AGCATCAAGA TTAAAAGAGT TTTTTAATTT TATAAACAAA AATTGTAAAG 2000
GCATACGAAG GATTCATCAA TTAACTAGAA ATGAAGTTGA GCAATATTTT AATTATATTA ATTTAAAAGG TTTAAAATCT AGTACCGTAA CCGGACGAAT 2100
ATCTACATTA GATGTTTTTT TTACTACAAT TCAAAGGTAT GACTGGAAGG ATACACCTTC TAAAATCCTT ATCTTTCAAG AAGATTACCC TAAAGTGCCG 2200
AAGGCACTAC CACGCTATAT TGATGAACAT ATACTGGAAC AATTAAATGG GAAATTAGAT AAATTGGAAC CTTATATTGC TACAATGATC ATGGTACTTC 2300
AAGAATGCGG AATGCGAATC AGTGAACTTT GTACATTGAA AAAAGGGAGC GTCATAACCG ATAAAGAAGG GGATTGTTTT TTAAAGTATT ATCAATGGAA 2400
AATGAAGAAA GAGCATATCA TTCCTATTTC AAAAGAAATT GCTGCATTGA TATTAGTTCA AGAGCAAAGA GTGGCTGATG AACTCGATGA TGGATGTGTA 2500
TATGTATTTC CCCGAAAAGA CGGCTCGCCA TTGAAGCAAG ATACCTTTAG GGTTAAATTA AATGAATTAG CTTATGAAGA AAAGATAACG GACAGCAAAG 2600
GAGAAATCTT TCGGTTTCAT GCTCATGCCT TTCGGCATAC AGTTGGCACA AGAATGATAA ATAACGGAGT GCCACAGCAT ATTGTCCAGA AATTCTTGGG 2700
TCACGAATCA CCGGAAATGA CGGCGAGATA TGCACATATT TTTGATGAAA CTCTTAAGAA GGAATTTACG AAATTCAAGG AAACCTTAGT AACGAATAAC 2800
GGTAACATTC TGGATTTAAG TGAGGAAAAT ACTGAAGCAG ACAATACAGA TCTTCAATGG TTTAAAAAGA ATATCAATGC ACAAGCACTT CCTAACGGTT 2900
ACTGTCGCTT ACCAGTAATT GCTGGACCCT GCCCTCACGC GAATGCTTGT TTAGATTGTA CGAACTTCTG TACAAGTAAA CAATTTCTAA ATGAACATGA 3000
GGATCACTTA AAACGAACGA AGGAAGTACT GAATAGGGCT AAACAGAACC AATGGCAGCG TCAGGTTGAA ACTAACGAAC GTGTTAAGAT TAGATTAGAG 3100
CAGATTATTC ATTCGTTAAA GGAGACGAAT TAAGATGACT AGAAGGAGTA ACACAACTGC CATAATTCAA CTATCAAAAG AAAAGTCGGA GAACACAAGA 3200
ATTAGGGTTG AAAAGACAAT TTCAGAGATG GCATTGAAAA AAGAGAGGAT TAATTTTAAT TCTGTTGCAC AAAAGGCAAA TGTTTCAAAG TCATGGCTTT 3300
ATAAACAAAA AGGCATCAGA ACTAGGGTGG AGACCTTAAG AGGGATGCAA ATAAGTGGAG TAGTGCCTCG TAAACCAAGT AAAAGTCCCC GTTCAGAGGA 3400
TGTATTAATA AAGACCTTAA AAAGCCGTAT AAAGGCACTA GAAGAAGAGA ACGAACAATT AAAGGATCAA GTTCAAAAAT TACATGGCAA GCTGTTTTAG 3500
CGTCAGAACT AATATGGCGT TCGGATTAGT GTGAACATTC GCTATGAGTA TGTGTTGAAA TAAACTTATG AAGTATAATT TACGAGATCG ATTTTCAACA 3600
ATCGGGCCGT ATTGTTGAAT AACATCTAGA TATCTTGGTT CTTCTTTGAA GAGGAAGAGA TTGCGAAATA CAGTACTTAA AGTAACGGGT CAGGTTTGCG 3700
GAAGAAAGAC TCATACGTAT ATAAATAAAC AAGTCCTTCG TATTATTTGA AGGACTTGTT ATTTCACTCT TCATTAATTG TAATAGTTTC ACTTGCTTTA 3800
TGATCAGGTT CTCCGTGGCC AGGTCCGAAC AAGTTTAATA TTACAACTCC TGCAAGAATT AGTGTAATTC CTGCAATGCT AGCCATGTTA AGTTTTTCTT 3900
TCCAAATTAA AACTGAGATT ATTGTGGTTA AAACAAGTCC TAAACCTGAC CATAATGAAT ATGCAGTGTT TAAGGGGATT GTTTTTAGCG ATAATGATAA 4000
AAAGAAAAAA GAAACAACGA AAGCTATTAT TACCCCTATT GTAGGAAAGA GTTTTGAAAA GCCTTCAGAT GCTTTTAATA AGGAAGAGCC AATAATTTCC 4100
CCCACTATTG CAAGTGCTAA ATATAGATAT GACATTGTTA TTCGCCCTCC TGAATCATCA TGATTAATTC GTCAAAAATT TGTTTTTTTA CTTCTTCGTT 4200
TAATGGTGCA ATTTCAAATA TTTCCGAGAA CCATAGACCA TCTATTAATA ATCTTGCCAT TGTTATTTTG AGTGGATCAA TCCCATCGTT TAGTAACTTG 4300
GTATGCAAAA TATCGTATTT TTGCTTGTAA TCATCCAATA AATCTGGATT TATAAACATA GCAGCCATTA GTGCTGAGCT TAGATTTTTG TTGTTGTTAT 4400
TATCTAAATC GAATAATGTT GTATTAATAT AAGCTCTATT CCATTTTCCT GTTTCTTTAC TATCCTTATT AACTAACGTT TTAATGCTTT CGAAAAAATT 4500
ATTTGTCCAA TCTTCCACCA TTCCTTTAAT TAATGCTTCT TTACTAGGGT AATGGTATAA TAATCCGCCT TTACTAACAC CAGCCCTTTG GGCAACCGCC 4600
TCTAAAGTAA GTTTTACAAC TCCTTCTTCT TTCACAATTT CAGACGCAGC AGTCAATAAA TTATTTTTTT TTATTAGTAT GTTTTGAAAT AGACATAATA 4700
ACCTCCAGAA ATTCAATATA TTAATATTAT ACCGTCCAGA CGGTTTTTTG TCAATCGAAT AATGTTTTTT TGTTTTATTG CTGCTCCAAA TAAAATATGT 4800
GGTTTGGTTA ATATTAAAAA TTAATATCAG TTTGCAAAGA ATTACCCTAA ATCTAACGTG GGCTTAACTT GTACCAGTGC TGAGTAATAA TCTTCAACTA 4900
ACGGGAGCGA TTGTTGCAGA TCAAAAGTCT AATTCCTCGA TAAAATATAA CGAGGAGTTA GGTTTTTTTT TGTGGTACAT TCTTATTGAC TGTAATCAAT 5000
TGTCATCTAA CAATTATATT GTATTTTTCC GTTTGATTTA ATGCGTTAAA TATATGTCCT TAAAGTAAAA GTATTGATGT TAATGGATTT TTAGTAGTTT 5100
ACTCTTGATA AAATCCG
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| ORFs |
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| Gene Name |
Associated TE |
Coordinates |
Class |
Sub Class |
Orientation |
| tnpA |
Tn6188 |
132-1217 |
Transposase |
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+ |
| tnpB |
Tn6188 |
1220-3133 |
Transposase |
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+ |
| tnpC |
Tn6188 |
3135-3500 |
Accessory Gene |
Helper |
+ |
| qacH (ARO:3003836) |
Tn6188 |
3764-4135 |
Passenger Gene |
Antibiotic Resistance |
- |
| AUH55373.1 |
Tn6188 |
4138-4656 |
Passenger Gene |
Hypothetical |
- |
| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| tnpA |
TnpA |
Tn6188 |
1086 |
132-1217 |
+ |
| Class: | Transposase |
Protein Sequence:
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MKVQKVIVEE KPYPLYILLD KEFEVIEPVK RFIKYLDNTG KAPNTIKTYC YHLKLFYEFM SQRGIGLEDL KFEEMSNFVG WLRNPTGDVK VITLQPKKAK
REETSVNAIL NAITSFLEYL NRTEDFKAID MTKEARGRNF KGFLHHISKG KSYKKNILKL RVKKKLVQVL EHEQVKAIID ACHTKRDKLL IMLMYEGGLR
IGEVLSLRIE DISTWDNLIN ITPRDHNENG AYIKLRKERT IDVSKELMAL YTDYLVHEYG EDLEHDYIFI NLKESYFGKP LKYQSVLDLI RRLGKRTGIT
FTAHMLRHTH ATELIRSGWD AAYVQKRLGH AHVQTTLDTY VHLSDQDMKN EYKAYLQGRE T
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| tnpB |
TnpB |
Tn6188 |
1914 |
1220-3133 |
+ |
| Class: | Transposase |
Protein Sequence:
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MKFPSVATNR KLVTSTEINK KISDMTSVLQ GFWAADRWDI RICPHPSAIE LSKNPSLKNR WVNFDKVENI WLKTELKYFY YVHLNNGTWN AKSVWIRKGT
VISRMLGFLN LNYPDITSIT EVPIKKALSE YRTYLAEQGI RTTTTNYKLD INQKKIPVYA NSYYVTNLKQ FMEFYEDFYF DGDEWEKDVW NRRKLSLSED
KVNPTSYEYT INFKGFENDY FKELVKRYCK LMLNTRSFSH VVDTASRLKE FFNFINKNCK GIRRIHQLTR NEVEQYFNYI NLKGLKSSTV TGRISTLDVF
FTTIQRYDWK DTPSKILIFQ EDYPKVPKAL PRYIDEHILE QLNGKLDKLE PYIATMIMVL QECGMRISEL CTLKKGSVIT DKEGDCFLKY YQWKMKKEHI
IPISKEIAAL ILVQEQRVAD ELDDGCVYVF PRKDGSPLKQ DTFRVKLNEL AYEEKITDSK GEIFRFHAHA FRHTVGTRMI NNGVPQHIVQ KFLGHESPEM
TARYAHIFDE TLKKEFTKFK ETLVTNNGNI LDLSEENTEA DNTDLQWFKK NINAQALPNG YCRLPVIAGP CPHANACLDC TNFCTSKQFL NEHEDHLKRT
KEVLNRAKQN QWQRQVETNE RVKIRLEQII HSLKETN
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| tnpC |
TnpC |
Tn6188 |
366 |
3135-3500 |
+ |
| Class: | Accessory Gene |
| Sub Class: | Helper |
| Sequence Family: | Tn554_family |
| Comment: | target specificity and orientation |
Protein Sequence:
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MTRRSNTTAI IQLSKEKSEN TRIRVEKTIS EMALKKERIN FNSVAQKANV SKSWLYKQKG IRTRVETLRG MQISGVVPRK PSKSPRSEDV LIKTLKSRIK
ALEEENEQLK DQVQKLHGKL F
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| qacH (ARO:3003836) |
QacH |
Tn6188 |
372 |
3764-4135 |
- |
| Class: | Passenger Gene |
| Sub Class: | Antibiotic Resistance |
| Function: | antibiotic efflux (ARO:0010000) |
| Target: | quaternary ammonium salts |
| Sequence Family: | small multidrug resistance (SMR) antibiotic efflux pump (ARO:0010003) |
| Comment: | subunit of the qac multidrug efflux pump||loose match to reference sequence for ARO:3003836 (bitscore:117) |
Protein Sequence:
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MSYLYLALAI VGEIIGSSLL KASEGFSKLF PTIGVIIAFV VSFFFLSLSL KTIPLNTAYS LWSGLGLVLT TIISVLIWKE KLNMASIAGI TLILAGVVIL
NLFGPGHGEP DHKASETITI NEE
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| AUH55373.1 |
AUH55373.1 |
Tn6188 |
519 |
4138-4656 |
- |
| Class: | Passenger Gene |
| Sub Class: | Hypothetical |
| Comment: | tetR family trancription regulator |
Protein Sequence:
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MTAASEIVKE EGVVKLTLEA VAQRAGVSKG GLLYHYPSKE ALIKGMVEDW TNNFFESIKT LVNKDSKETG KWNRAYINTT LFDLDNNNNK NLSSALMAAM
FINPDLLDDY KQKYDILHTK LLNDGIDPLK ITMARLLIDG LWFSEIFEIA PLNEEVKKQI FDELIMMIQE GE
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| References |
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Müller A, Rychli K, Muhterem-Uyar M, Zaiser A, Stessl B, Guinane CM, Cotter PD, Wagner M, Schmitz-Esser S. Tn6188. PLoS One. 2013 Oct 2;8(10):e76835. doi: 10.1371/journal.pone.0076835. eCollection 2013. PubMed ID: 24098567
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