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Internal Transposable Elements | |
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| Name: Tn6007 |
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| Family: Tn402 |
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| Evidence of Transposition: no |
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| Host |
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| Host Organism: | Enterobacter cloacae JKB7 | Molecular Source: | Plasmid pUB307 |
| Place of Origin: | Australia | Date of Isolation: | 2008 |
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| Map |
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| Terminal Inverted Repeats (IR) |
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| Sequence |
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--------10 --------20 --------30 --------40 --------50 --------60 --------70 --------80 --------90 -------100
TGTCATTTTC AGAAGACGAC TGCACCAATT GACGGGGCGT AACGCCAGGT GTGCAGTCGG CTCCTGACCA CGCAATATCA GAAGTCATCT GCACCAATCT 100
CGACTATGCT CAATACTCGT GTGCACCAAA GCGAGGTGTG AGCATGGCGT CAGACACATT ACCAATTGCC GAGCAGGGCG TGGCCACCCT GCCCGATGCG 200
GCATGGGCAC AGGCCCGGCA CCGGACCGAA ATCATCGGGC CGCTGGCAGC GCTTGAAGTG GTTGGGCATG AAGCCGCCGA TGCCGCTGCT CAAGCGCTGG 300
GCCTATCCAG GCGGCAGGTG TATGTCCTGA TCCGGCGTGC CCGGCAAGGT GCTGGGTTTG TGACGGACCT GGTTCCCGGC CAGTCCGGCG GCGGAAAAGG 400
CAAGGGACGC TTGCCGGAAT CAGTTGAGCG CATCATCCGC GAGTTGCTGC AAAAGCGCTT CCTGACCAAG CAGAAGCGTA GCCTGGCGGC GTTCCACCGC 500
GAGGTCGCGC AGGCTTGCAA AGCGCAAAAG CTACGGGTGC CGGCGCGCAA CACTTTGGCC CTGCGGATCG CCGGCCTCGA CCCGCTCAAG GCCACTCGCC 600
GCCGGGAAGG TCAGGATGCG TCCCGCAGCC TGCAAGGTGT CGGTGGTGAG CCTCCCGCCG TGACCGCGCC ACTGGAACAA GTGCAGATTG ATCACACGGT 700
CATCGACCTG ATCGTGGTGG ACGAGCGCGA CCGGCAACCG ATTGGCCGTC CGTATCTGAC CATCGCCATC GACGTGTTTA CCCGCTGCGT GCTCGGCATG 800
GTCGTCACGC TGGAAGCGCC GTCATCTGTT TCGGTCGGCC TGTGCCTTGT GCATGTCGCC TGCGACAAGC GTCCCTGGCT GGAGGGTCTG AATATAGAAA 900
TGGATTGGCC GATGAGCGGC AAGCCCAGGC TGCTCTACTT GGACAACGCG GCCGAGTTCA AGAGCGAGGC GCTGCGCCGT GGCTGCGAGC AGCACGGCAT 1000
CCGGTTGGAC TATCGTCCGC CAGGGCAGCC GCACTACGGC GGCATCGTGG AACGGATCAT CGGTACGGCG ATGCAGATGA TCCACGATGA ATTGCCAGGG 1100
ACGACCTTCT CCAACCCTGA CCAGCGCGGG GACTACGATT CCGAAAACAA GGCCGCCCTG ACATTGCGTG AGCTGGAGCG CTGGCTCACG TTGGCGGTGG 1200
GCACCTATCA CGGCTCTGTG CACAACGGCC TGCTTCAGCC GCCGGCGGCG CGCTGGTCAG AAGCCGTGGC GCGTGTCGGT GTACCGGCTG TCGTCACCCG 1300
CGCCTTGGCT TTTTTGGTCG ATTTCCTGCC CATCATTCGC CGTACTCTGA CTCGCACCGG CTTTGTCATC GACCACATTC ACTACTACGC CGATGCGCTC 1400
AAACCGTGGA TCGCACGACG CGACCGCTTG CCCGCTTTCC TGATCCGGCG CGACCCGCGT GACATCAGCC GTATCTGGGT GCTGGAACCG GAGGGGCAGC 1500
ATTACCTGGA AATCCCCTAC CGTACCTTGT CGCACCCGGC TGTCACCCTC TGGGAACAAC GGCAGGCGCT GACGAAATTG CGGCAGCAGG GACGCGAACA 1600
GGTGGATGAG TCGGCGCTGT TCCGCATGAT CGGGCAGATG CGCGAGATCG TGACCACCGC ACAGAAGGCC ACGCGCAAGG CGCGGCGCGA CGCGGATCGA 1700
CGCCAGCACC TCAAGGCATC GCCTCCGCCG GACAAGCCGA TTCCGCCGAA AACGGACGTT GCTGATCCGC AGGCAGACAA CCTGCCTCCG GCCAAACCGT 1800
TCGACCAGAT CGAGGAGTGG TAGCCGTGGA CGAATATCCC ATCATCGACT TGTCACACCT GCTGCCAGCT GCACAGGGGC TGGCTCGGCT GCCGGCGGAC 1900
GAGCGCATCC AGCGCCTTCG CGCCGACCGC TGGATCGGCT ACCCGCGCGC GGTCGAGGCG CTGAACCGGC TGGAAACCCT GTATGCGTGG CCAAACAAGC 2000
AACGCATGCC CAACCTGCTG CTGGTTGGCC CGACCAACAA CGGCAAGTCG ATGATCATCG AGAAATTCCG GCGCACGCAT CCGGCCAGCT CCGACGCGGA 2100
CCAGGAACAC ATGCCGGTGC TGGTCGTGCA GATGCCGTCC GAACCGTCGG TGATCCGCTT CTACGTCGCG CTACTTGCCG CGATGGGGGC ACCATTGCGC 2200
CCGCGCCCAC GGCTGCCGGA AATGGAGCAA CTGGCGCTGG CACTGCTGCG CAAGGTCGGC GTGCGCATGC TGGTGATCGA CGAGCTGCAC AACGTCTTGG 2300
CCGGCAACAG CGTCAACCGG CGGGAATTTC TCAACCTGCT GCGCTTCCTC GGCAATGAGC TGCGCATCCC ATTGGTCGGG GTCGGCACGC GCGACGCCTA 2400
CCTGGCCATC CGCTCGGATG ACCAATTGGA AAACCGCTTC GAGCCCATGA TGCTGCCGGT GTGGGAGGCC AACGACGATT GCTGCTCACT GCTGGCCAGC 2500
TTCGCCGCTT CGCTTCCATT GCGGCGACCC TCGTCGATTG CCACGCTGGA CATGGCCCGC TACCTGCTCA CACGCAGCGA GGGCACCATC GGCGAACTGG 2600
CGCACTTGCT GATGGCGGCG GCCCTCGTCG CCGTGGAGAG CGGCGAGGAA GCGATCAACC ACCGCACGCT CAGCATGGCC GATTACACCG GCCCAAGCGA 2700
GCGGCGTCGG CAATTCGAGC GGGAACTGAT GTGAAGCCAG CGCCACGCTG GCCGCTGCAT CCGGCTCCCA AGGAAGGCGA AGCCTTGTCT TCATGGCTCA 2800
ACCGCGTGGC CCTTTGCTAT CACATGGAGG TGTCCGACCT GCTGGAGCAC GATCTTGGTC ACGGCCAGGT TGATGACCTG GATACCGCGC CACCACTGTC 2900
GCTGCTGATG ATGCTCTTCC AGCGGAGCGG CATCGAGCTG GACCGGCTGC GTTGCATGAG TTTCGCCGGC TGGGTGCCTT GGCTACTGGA TAGCCTTGAT 3000
GATCAGATTC CAGACGCATT GGAAACCTAT GCGTTCCAGC TCTCGGTGCT GCTGCCGAAA CTCCGCCGTA GGACGCGATC CATCACGAAC TGGCGTGCCT 3100
GGCTGCCCAG CCAGCCGATA CATCGCGCCT GTCCGCTCTG TCTGAACGAC CCGGCAAACC AAGCCGTACT GCTTGCATGG AAGCTGCCCC TGATGCTGAG 3200
CTGCCCGCTG CATGGTTGCT GGCTGGAATC CTATTGGGGC GTGCCTGGGC GGTTTCTCGG CTGGGATAAC GCCGACACTG CGCCGCGCAC CGCCAGCGAC 3300
GCGATTGCAG TGATGGACCG GCGTACCTGG CAGGCACTGA CGACCGGCCA TGTGGAGCTG CCGCGCCGAC GCATCCACGC TGGATTGTGG TTTCGGCTAA 3400
TACGCACGCT GCTCGATGAG CTGAACACCC CGCTTTCGAC GTGCGGAACC TGCGCGGGGT ATCTCCGCCA AGTATGGGAA GGCTGCGGGC ATCCGCTGCG 3500
TGCTGGGCAA AGTCTGTGGC GACCGTATGA AACCCTGAAC CCGGCAGTAC GATTGCAGAT GCTGGAGGCG GCGGCAACGG CAATCAGCTT GATTGAGGTG 3600
AGGGATATTA GCCCGCCAGG CGAGCATGCA AAGCTGTTCT GGTCCGAGCC CCAAACCGGG TTCACCAGTG GCCTGCCGGC GAAAGCGCTG AAGCCCGAAC 3700
CCGTCGATCA CTGGCAGCGT GCGGTCAAGG CCATTGATGA CGCCATCATT GAAGCGCGGC ACGACCCCGA GACGGCACGC TCGCTGTTCG CGTTGGCTTC 3800
CTATGGTCGG CGCGACCCCG CTTCCCTGGA ACAGTTGCGC GCTACCTTCG CGAAGGAAGG CATCCCCACG GAATTTTTGT CACATTACGA GCCTGATGAG 3900
CCCTTTGCAT GTCTTAGACA GAATGACGGG TTAAGTGACA AATTTTGACG ACCAGAACTT TCCGGTTCAC ACTGTCACAT AATCGAACGT ATACGTGACG 4000
GGTGAAAAGG TGCTGATCGG CTACATGCGG GTATCGAAGG CGGACGGATC CCAGTCCACC AATTTGCAAC GCGATGCGCT CATCGCCGCT GGTGTGAGCC 4100
TTGCGCACCT TTACGAGGAT CTGGCCTCGG GCAGGCGCGA TGATCGCCCA GGGTTGGCTG CTTGCCTGAA GGCGCTTCGT GAAGGGGACA CGCTGATCGT 4200
GTGGAAGCTC GATCGGCTTG GCCGTGATCT GCGCCACCTG ATCAACACCG TGCACGACCT AACTGCGCGT AGCGTGGGCC TGAAGGTCCT GACCGGTCAC 4300
GGTGCGGCGG TCGACACGAC GACTGCCGCC GGCAAGCTTG TGTTCGGTAT TTTTGCCGCG CTGGCCGAGT TCGAGCGTGA GTTGATTTCC GAGCGAACAG 4400
TCGCTGGACT TATCTCGGCG CGCGCTCGCG GCAGGAAAGG GGGGCGCCCC TTCAAGATGA CCGCCGCCAA GCTACGCCTG GCGATGGCCA GCATGGGGCA 4500
ACCGGAAACC AAGGTGGGCG ATCTCTGCGA AGAACTCGGG ATTACCCGGC AGACGCTCTA CCGGCACGTG TCGCCCAAGG GCGAACTGCG GCCAGACGGC 4600
GTAAAGCTGC TCTCCCTCGG TTCAGCCGCA TAAATGGAGG CGACCTGGAA CGGGGCGCTG TTCAGTGCGG CAACGATCCG ATTACCGGTG TCGACCCAGA 4700
GCAGCCGTAG AGCTTTTGGG AAAGCTGTCG TTCAACGTTT GACGTGAGGG GCCGCCGTAG CGGCGAAGCC GCGAAGGGAA CCCGCAAGCG CAGCTTGTGG 4800
GCGGTCCCTC TCGACGGAAT GGTTAGATGC GACCGTTTTA GTGAACACTT GCCTTAGATA GCAAGTTGAG CACAGCAACG CCGCTGATAA TGAAGCCGAC 4900
ACCAACAAAT CCCCACATAT CTAGTTTTTG ACCATGCAAA ACCCATGCAA TCGCAGTGAC CAAGACGATC CCGAGGCCCG ACCAAACTGC GTAGGCGATT 5000
CCAACAGGAA TCGATTTGAG TGTCAGCGAC AGGAAATAAA AAGCAGCAGC GTATCCCGCT ACGACGATAA AAGACGGTAC TAACCTAGTA AAGCCCTCAC 5100
TAGACTTGAG CGCAGAGGTT GCAATGACCT CAAAAATAAT GGCCGTAGCC AGAAATAACC AATTTTTCAA AATATTTCTC CATGGAGTTC CGCGAAGAAA 5200
TTTTAGGTTC GATTTAAGAA AAAAAAACAG TCTTGTTGCT GGCCGAAATT TGTGCGCACA GCAAAGCATC TAACGCTGGA GTTAAGCCGC GGCGCGTAGC 5300
GCCGTCGGCT TGAACGACTT GTTATACAAA TTTTGCTGGT AACCAGATTG ACCATTTTGG AAATCAATTG TTTTTTACAA GATGAATAAA CCTATCAACA 5400
TCGGCTTGGT AATCTTGAGA ATTGAAACCG TTTTCGCAGT TTGCGTGAAC ATAGCCGCCA TAGCCCATGC CAAGATATCT GAAGGTATCT TTAAATGAAT 5500
TGAGAAATGA GCTATCAGCA TCGCTGCTAA TGGATGTGCA AACAACAAAA CCTGTTTTAC TGCGCAGCCG CCTACCAATA TCCTTTAGCT CATCAACATC 5600
CAGAAAATCC GATGTTCTAT CAATAAATAC CTTCATTTGA GCACTTGGGC CGTACCAATA AACTGGCGTT GCCAAAATTA TATTCTCGTA ATCTAGCAAT 5700
TGATTCATCA CAGAAAGAAA ATCATCGCCT ATGTTTTTGT GATCATAGTC ATAGGGTGAT ATGTCTTTAT CCAACAAATT GATTACACCA ATATCTAGCT 5800
CAGAAGAGAT CCAATCTATA AGTCTACCTG TATTGCCATT CCTTCTGGCA CTCGCAAATA CTGCTATTGT TTTGCTCACT GCTGACTCCT TTCATTTGTA 5900
TAACTTTGTT TTAGGGCGAC TGCCCTGCTG CGTAACATCG TTGCTGCTCC ATAACATCAA ACATCGACCC ACGGCGTAAC GCGCTTGCTG CTTGGATGCC 6000
CGAGGCATAG ACTGTACAAA AAAACAGTCA TAACAAGCCA TGAAAACCGC CACTGCGCCG TTACCACCGC TGCGTTCGGT CAAGGTTCTG GACCAGTTGC 6100
GTGAGCGCAT ACGCTACTTG CATTACAGTT TACGAACCGA ACAGGCTTAT GTCCACTGGG TTCGTGCCTT CATCCGTTTC CACGGTGTGC GTCACCCGGC 6200
AACCTTGGGC AGCAGCGAAG TCGAGGCATT TCTGTCCTGG CTGGCGAACG AGCGCAAGGT TTCGGTCTCC ACGCATCGTC AGGCATTGGC GGCCTTGCTG 6300
TTCTTCTACG GCAAGGTGCT GTGCACGGAT CTGCCCTGGC TTCAGGAGAT CGGAAGACCT CGGCCGTCGC GGCGCTTGCC GGTGGTGCTG ACCCCGGATG 6400
AAGTGGTTCG CATCCTCGGT TTTCTGGAAG GCGAGCATCG TTTGTTCGCC CAGCTTCTGT ATGGAACGGG CATGCGGATC AGTGAGGGTT TGCAACTGCG 6500
GGTCAAGGAT CTGGATTTCG ATCACGGCAC GATCATCGTG CGGGAGGGCA AGGGCTCCAA GGATCGGGCC TTGATGTTAC CCGAGAGCTT GGCACCCAGC 6600
CTGCGCGAGC AGCTGTCGCG TGCACGGGCA TGGTGGCTGA AGGACCAGGC CGAGGGCCGC AGCGGCGTTG CGCTTCCCGA CGCCCTTGAG CGGAAGTATC 6700
CGCGCGCCGG GCATTCCTGG CCGTGGTTCT GGGTTTTTGC GCAGCACACG CATTCGACCG ATCCACGGAG CGGTGTCGTG CGTCGCCATC ACATGTATGA 6800
CCAGACCTTT CAGCGCGCCT TCAAACGTGC CGTAGAACAA GCAGGCATCA CGAAGCCCGC CACACCGCAC ACCCTCCGCC ACTCGTTCGC GACGGCCTTG 6900
CTCCGCAGCG GTTACGACAT TCGAACCGTG CAGGATCTGC TCGGCCATTC CGACGTCTCT ACGACGATGA TTTACACGCA TGTGCTGAAA GTTGGCGGTG 7000
CCGGAGTGCG CTCACCGCTT GATGCGCTGC CGCCCCTCAC TAGTGAGAGG TAGGGCAGCG CAAGTCAATC CTGGCGGATT CACTACCCCT GCGCGAAGGC 7100
CATCGGTGCC GCATCGAACG GCCGGTTGCG GAAAGTCCTC CCTGCGTCCG CTGATGGCCG GCAGCAGCCC GTCGTTGCCT GATGGATCCA ACCCCTCCGC 7200
TGCTATAGTG CAGTCGGCTT CTGACGTTCA GTGCAGCCGT CTTCTGAAAA CGACA
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| Recombination Sites |
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| Name |
Coordinates |
Gene |
Sequence |
| repeat t3 |
78-97 |
20 |
TCAGAAGTCA TCTGCACCAA |
| r4 |
3877-3890 |
14 |
TTGTCACATT ACGA |
| r3 |
3928-3941 |
14 |
GGGTTAAGTG ACAA |
| res |
3969-4003 |
35 |
ACACTGTCAC ATAATCGAAC GTATACGTGA CGGGT |
| r2 |
3972-3985 |
14 |
CTGTCACATA ATCG |
| r1 |
3988-4001 |
14 |
CGTATACGTG ACGG |
| attC qacL core |
4736-4828 |
93 |
CGTTTGACGT GAGGGGCCGC CGTAGCGGCG AAGCCGCGAA GGGAACCCGC AAGCGCAGCT
TGTGGGCGGT CCCTCTCGAC GGAATGGTTA GAT |
| attC JK007 core |
5274-5327 |
54 |
CGCTGGAGTT AAGCCGCGGC GCGTAGCGCC GTCGGCTTGA ACGACTTGTT ATAC |
| attI |
5904-5959 |
56 |
CTTTGTTTTA GGGCGACTGC CCTGCTGCGT AACATCGTTG CTGCTCCATA ACATCA |
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| ORFs |
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| Gene Name |
Associated TE |
Coordinates |
Class |
Sub Class |
Orientation |
| tniA |
Tn6007 |
144-1823 |
Transposase |
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+ |
| tniB |
Tn6007 |
1826-2734 |
Accessory Gene |
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+ |
| tniQ |
Tn6007 |
2731-3948 |
Accessory Gene |
Target Site Selection |
+ |
| tniR |
Tn6007 |
4010-4633 |
Accessory Gene |
Resolvase |
+ |
| qacL (ARO:3005098) |
Tn6007 |
4838-5170 |
Passenger Gene |
Antibiotic Resistance |
- |
| NAD(P)H-dependent oxidoreductase |
Tn6007 |
5364-5879 |
Passenger Gene |
Other |
- |
| intI1 |
Tn6007 |
6040-7053 |
Integron Integrase |
Class 1 |
+ |
| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| tniA |
TniA |
Tn6007 |
1680 |
144-1823 |
+ |
| Class: | Transposase |
| Transpoase Chemistry: | DDE |
| Comment: | Tn402-like || homologous to TnsB of Tn7 || original is nonfunctional due to 1 bp deletion |
Protein Sequence:
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MASDTLPIAE QGVATLPDAA WAQARHRTEI IGPLAALEVV GHEAADAAAQ ALGLSRRQVY VLIRRARQGA GFVTDLVPGQ SGGGKGKGRL PESVERIIRE
LLQKRFLTKQ KRSLAAFHRE VAQACKAQKL RVPARNTLAL RIAGLDPLKA TRRREGQDAS RSLQGVGGEP PAVTAPLEQV QIDHTVIDLI VVDERDRQPI
GRPYLTIAID VFTRCVLGMV VTLEAPSSVS VGLCLVHVAC DKRPWLEGLN IEMDWPMSGK PRLLYLDNAA EFKSEALRRG CEQHGIRLDY RPPGQPHYGG
IVERIIGTAM QMIHDELPGT TFSNPDQRGD YDSENKAALT LRELERWLTL AVGTYHGSVH NGLLQPPAAR WSEAVARVGV PAVVTRALAF LVDFLPIIRR
TLTRTGFVID HIHYYADALK PWIARRDRLP AFLIRRDPRD ISRIWVLEPE GQHYLEIPYR TLSHPAVTLW EQRQALTKLR QQGREQVDES ALFRMIGQMR
EIVTTAQKAT RKARRDADRR QHLKASPPPD KPIPPKTDVA DPQADNLPPA KPFDQIEEW
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| tniB |
TniB |
Tn6007 |
909 |
1826-2734 |
+ |
| Class: | Accessory Gene |
| Transpoase Chemistry: | Serine |
| Comment: | homologous to TnsC protein of Tn7 putative ATP-binding protein |
Protein Sequence:
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MDEYPIIDLS HLLPAAQGLA RLPADERIQR LRADRWIGYP RAVEALNRLE TLYAWPNKQR MPNLLLVGPT NNGKSMIIEK FRRTHPASSD ADQEHMPVLV
VQMPSEPSVI RFYVALLAAM GAPLRPRPRL PEMEQLALAL LRKVGVRMLV IDELHNVLAG NSVNRREFLN LLRFLGNELR IPLVGVGTRD AYLAIRSDDQ
LENRFEPMML PVWEANDDCC SLLASFAASL PLRRPSSIAT LDMARYLLTR SEGTIGELAH LLMAAALVAV ESGEEAINHR TLSMADYTGP SERRRQFERE
LM
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| tniQ |
TniQ |
Tn6007 |
1218 |
2731-3948 |
+ |
| Class: | Accessory Gene |
| Sub Class: | Target Site Selection |
| Comment: | Tn402-like || Protein: ACE81793.1 |
Protein Sequence:
|
VKPAPRWPLH PAPKEGEALS SWLNRVALCY HMEVSDLLEH DLGHGQVDDL DTAPPLSLLM MLFQRSGIEL DRLRCMSFAG WVPWLLDSLD DQIPDALETY
AFQLSVLLPK LRRRTRSITN WRAWLPSQPI HRACPLCLND PANQAVLLAW KLPLMLSCPL HGCWLESYWG VPGRFLGWDN ADTAPRTASD AIAVMDRRTW
QALTTGHVEL PRRRIHAGLW FRLIRTLLDE LNTPLSTCGT CAGYLRQVWE GCGHPLRAGQ SLWRPYETLN PAVRLQMLEA AATAISLIEV RDISPPGEHA
KLFWSEPQTG FTSGLPAKAL KPEPVDHWQR AVKAIDDAII EARHDPETAR SLFALASYGR RDPASLEQLR ATFAKEGIPT EFLSHYEPDE PFACLRQNDG
LSDKF
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| tniR |
TniR |
Tn6007 |
624 |
4010-4633 |
+ |
| Class: | Accessory Gene |
| Sub Class: | Resolvase |
| Transpoase Chemistry: | Serine |
| Sequence Family: | Serine Site-Specific Recombinase |
| Comment: | resolution of cointegrates || Protein: ACE81792.1 || identical to tniR (Tn1721) |
Protein Sequence:
|
MLIGYMRVSK ADGSQSTNLQ RDALIAAGVS LAHLYEDLAS GRRDDRPGLA ACLKALREGD TLIVWKLDRL GRDLRHLINT VHDLTARSVG LKVLTGHGAA
VDTTTAAGKL VFGIFAALAE FERELISERT VAGLISARAR GRKGGRPFKM TAAKLRLAMA SMGQPETKVG DLCEELGITR QTLYRHVSPK GELRPDGVKL
LSLGSAA
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| qacL (ARO:3005098) |
QacL |
Tn6007 |
333 |
4838-5170 |
- |
| Class: | Passenger Gene |
| Sub Class: | Antibiotic Resistance |
| Function: | antibiotic efflux (ARO:0010000) |
| Target: | quaternary ammonium salts |
| Sequence Family: | small multidrug resistance (SMR) antibiotic efflux pump (ARO:0010003) |
| Comment: | subunit of the qac multidrug efflux pump||loose match to reference sequence for ARO:3005098 (bitscore:173) |
Protein Sequence:
|
MKNWLFLATA IIFEVIATSA LKSSEGFTRL VPSFIVVAGY AAAFYFLSLT LKSIPVGIAY AVWSGLGIVL VTAIAWVLHG QKLDMWGFVG VGFIISGVAV
LNLLSKASVH
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| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| NAD(P)H-dependent oxidoreductase |
NAD(P)H-dependent oxidoreductase |
Tn6007 |
516 |
5364-5879 |
- |
| Class: | Passenger Gene |
| Sub Class: | Other |
Protein Sequence:
|
MSKTIAVFAS ARRNGNTGRL IDWISSELDI GVINLLDKDI SPYDYDHKNI GDDFLSVMNQ LLDYENIILA TPVYWYGPSA QMKVFIDRTS DFLDVDELKD
IGRRLRSKTG FVVCTSISSD ADSSFLNSFK DTFRYLGMGY GGYVHANCEN GFNSQDYQAD VDRFIHLVKN N
|
| Gene Name |
Protein Name |
Associated TE |
Gene Length |
Coordinates |
Strand |
| intI1 |
IntI1 |
Tn6007 |
1014 |
6040-7053 |
+ |
| Class: | Integron Integrase |
| Sub Class: | Class 1 |
| Transpoase Chemistry: | Tyrosine |
| Sequence Family: | Class 1 Integron Tyrosine Integrase |
Protein Sequence:
|
MKTATAPLPP LRSVKVLDQL RERIRYLHYS LRTEQAYVHW VRAFIRFHGV RHPATLGSSE VEAFLSWLAN ERKVSVSTHR QALAALLFFY GKVLCTDLPW
LQEIGRPRPS RRLPVVLTPD EVVRILGFLE GEHRLFAQLL YGTGMRISEG LQLRVKDLDF DHGTIIVREG KGSKDRALML PESLAPSLRE QLSRARAWWL
KDQAEGRSGV ALPDALERKY PRAGHSWPWF WVFAQHTHST DPRSGVVRRH HMYDQTFQRA FKRAVEQAGI TKPATPHTLR HSFATALLRS GYDIRTVQDL
LGHSDVSTTM IYTHVLKVGG AGVRSPLDAL PPLTSER
|
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| Internal Repeat Elements |
|
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| Name |
Associated Mobile Element |
Coordinates |
Sequence (Top Strand) |
| repeat t2 |
Tn6007 |
50-67 |
ACACGTCAGC CGAGGACT |
| repeat t4 |
Tn6007 |
110-128 |
TCAATACTCG TGTGCACCA |
| repeat i4 |
Tn6007 |
7136-7154 |
AGGAGGGACG CAGGCGACT |
| repeat i3 |
Tn6007 |
7164-7182 |
CGTCGGGCAG CAACGGACT |
| repeat i2 |
Tn6007 |
7206-7224 |
ATCACGTCAG CCGAAGACT |
| IRi |
Tn6007 |
7223-7255 |
CTGCAAGTCA CGTCGGCAGA AGACTTTTGC TGT |
|
| References |
|
|
| 1. | Labbate M, Roy Chowdhury P, Stokes HW. A class 1 integron present in a human commensal has a hybrid transposition module compared to Tn402: evidence of interaction with mobile DNA from natural environments. J Bacteriol. 2008 Aug;190(15):5318-27. doi: 10.1128/JB.00199-08. Epub 2008 May 23. PubMed ID: 18502858
| | | 2. | Ghaly TM, ORCID: 0000-0002-5162-4054, Chow L, Asher AJ, Waldron LS, Gillings MR. Evolution of class 1 integrons: Mobilization and dispersal via food-borne bacteria. PLoS One. 2017 Jun 6;12(6):e0179169. doi: 10.1371/journal.pone.0179169. eCollection 2017. PubMed ID: 28586403
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